Evidence map›Paper›PMID 36199782›Full record

Trial reportComputational and mathematical methods in medicine2022

The Effects of Combuxil and Leizumab on Retinal Function and Serum Interleukin-17A in Premature Infants with Retinopathy.

Huixuan Ren, Gang Su, Shunian Xu, Li Zhou, Shanjun Cai

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huixuan RenOphthalmology, Department of Ophthalmology, Affiliated Hospital of Zunyi Medical University, Guizhou Provincial Eye Hospital, Guizhou Branch Center of National Clinical Research Center for Eye Diseases, Guizhou Provincial Key Laboratory of Characteristic Eye Diseases Characteristics, Zunyi, Guizhou 563003, China.
Gang SuOphthalmology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China.
Shunian XuOphthalmology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China.
Li ZhouOphthalmology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China.
Shanjun CaiOphthalmology, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China.ORCID https://orcid.org/0000-0002-5900-9881
Zunyi Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the effects of Compaximab and raizumab on retinal function and serum interleukin-17A level in retinopathy of prematurity. Methods: Sixty cases of retinopathy of prematurity treated in our hospital from February 2019 to April 2021 were selected. The patients were randomly divided into control group ( Results: Compared with the two groups, the curative effect of the research group 93.33% (28/30) was greater than that of the control group 66.67% (20/30), and the difference was statistically significant ( Conclusion: Intravitreal injection of razumab is an effective treatment for retinopathy of prematurity, which can effectively improve the retinal function of infants. The level of serum interleukin-17A can be reduced and intraocular pressure can be regulated, which is safe and effective.

Indexed as

Interleukin-17Retinopathy of PrematurityHumansInfantInfant, NewbornInfant, PrematureIntravitreal InjectionsRetinaInterleukin-17

Identifiers

PMID36199782
PMCPMC9529416
OpenAlexW4297107656

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.