Evidence map›Paper›PMID 36199754›Full record

ArticleBioMed research international2022

Studying the Anticancer Effects of Thymoquinone on Breast Cancer Cells through Natural Killer Cell Activity.

Huda F Alshaibi, Nouf A Aldarmahi, Nuha A Alkhattabi, Hadeil M Alsufiani, Nesrin I Tarbiah

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 9 citations in OpenAlex.

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  8. PeerJ · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Huda F AlshaibiBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0003-3739-8844
Nouf A AldarmahiBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Nuha A AlkhattabiBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-1629-1514
Hadeil M AlsufianiBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-8474-8985
Nesrin I TarbiahBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.ORCID https://orcid.org/0000-0002-8706-2663
King Abdulaziz University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer immunotherapy is quickly growing and can now be viewed as the "fifth column" of cancer treatment. In addition, cancer immunotherapy has shown promising results with different kinds of cancers and may be used as a complementary therapy with various types of treatments. Thus, "immuno-oncology" is showing astounding advantages. However, one of the main challenges that face this type of therapy is that cancer cells can evade immune system elimination through different mechanisms. Many studies were done to overcome this issue including adding immune stimulants to generate synergistic effects or by genetically modifying NK cells themselves to be stronger and more resistant.

Indexed as

Breast NeoplasmsNigella sativaBenzoquinonesFemaleGranzymesHumansInterferon-alphaKiller Cells, NaturalPerforinBenzoquinonesGranzymesInterferon-alphaPerforinthymoquinone

Identifiers

PMID36199754
PMCPMC9527111
OpenAlexW4296784399

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.