Evidence map›Paper›PMID 36199687›Full record

ReviewFrontiers in pharmacology2022

Biological activities of meroterpenoids isolated from different sources.

Neeraj Kumar Fuloria, Radhika K Raheja, Kaushal H Shah, Manisha J Oza, Yogesh A Kulkarni, Vetriselvan Subramaniyan, Mahendran Sekar, Shivkanya Fuloria

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Review
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  13. Comparative metabolic study of the chloroform fraction of threeJournal of enzyme inhibition and medicinal chemistry · 2024
    Article
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  18. Anticancer Effect of Mycotoxins FromInternational journal of microbiology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neeraj Kumar FuloriaFaculty of Pharmacy, AIMST University, Bedong, Malaysia.
Radhika K RahejaSVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India.
Kaushal H ShahSVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India.
Manisha J OzaSVKM's Dr. Bhanuben Nanavati College of Pharmacy, Mumbai, India.
Yogesh A KulkarniShobhaben Pratapbhai Patel School of Pharmacy & Technology Management, SVKM's NMIMS, Mumbai, India.
Vetriselvan SubramaniyanFaculty of Medicine, Bioscience and Nursing, MAHSA University, Selangor, Malaysia.
Mahendran SekarDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy and Health Sciences, Royal College of Medicine Perak, Universiti Kuala Lumpur, Ipoh, Malaysia.
Shivkanya FuloriaFaculty of Pharmacy, AIMST University, Bedong, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meroterpenoids are natural products synthesized by unicellular organisms such as bacteria and multicellular organisms such as fungi, plants, and animals, including those of marine origin. Structurally, these compounds exhibit a wide diversity depending upon the origin and the biosynthetic pathway they emerge from. This diversity in structural features imparts a wide spectrum of biological activity to meroterpenoids. Based on the biosynthetic pathway of origin, these compounds are either polyketide-terpenoids or non-polyketide terpenoids. The recent surge of interest in meroterpenoids has led to a systematic screening of these compounds for many biological actions. Different meroterpenoids have been recorded for a broad range of operations, such as anti-cholinesterase, COX-2 inhibitory, anti-leishmanial, anti-diabetic, anti-oxidative, anti-inflammatory, anti-neoplastic, anti-bacterial, antimalarial, anti-viral, anti-obesity, and insecticidal activity. Meroterpenoids also possess inhibitory activity against the expression of nitric oxide, TNF- α, and other inflammatory mediators. These compounds also show renal protective, cardioprotective, and neuroprotective activities. The present review includes literature from 1999 to date and discusses 590 biologically active meroterpenoids, of which 231 are from fungal sources, 212 are from various species of plants, and 147 are from marine sources such as algae and sponges.

Indexed as

anti-fungalanti-inflammatoryanti-microbialanti-oxidantanti-proliferativeanti-viralcytotoxicitymeroterpenoids

Identifiers

PMID36199687
PMCPMC9527340

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.