Evidence map›Paper›PMID 36199677›Full record

ArticleInternational journal of dermatology and venereology2022

Biofilm Alterations on the Stepwise Acquisition of Fluconazole-resistant

Na-Na Song, Guan-Yu Qian, Hai-Lin Zheng, Xiao-Wei Zhou, Huan Mei, Dong-Mei Li, Xiao-Fang Li, Wei-Da Liu

Abstract read
In one paragraph

Article in International journal of dermatology and venereology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Na-Na SongDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Guan-Yu QianDepartment of Dermatology, Xuzhou Tumor Hospital, Xuzhou, Jiangsu 221000, China.
Hai-Lin ZhengDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Xiao-Wei ZhouDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Huan MeiDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Dong-Mei LiDepartment of Microbiology & Immunology, Georgetown University Medical Center, Washington, DC 20057, USA.
Xiao-Fang LiDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.
Wei-Da LiuDepartment of Mycology, Hospital for Skin Diseases (Institute of Dermatology), Chinese Academy of Medical Sciences and Peking Union Medical College, Nanjing, Jiangsu 210042, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

By assessing and comparing the phenotypic changes on the stepwise acquisition of fluconazole resistant Methods: We performed antifungal susceptibility of five drugs (fluconazole, itraconazole, voriconazole, caspofungin and amphotericin B) to further verify the antifungal activity of the six isolates Results: Biofilm capability is enhanced for four drug- intermediate strains, whereas the initial susceptible strain and the final resistant strain are both poor in adherence, hyphal growth and biofilm formation. Conclusions: It was suggested that the biofilm formation ability were not absolutely related to the degree of fluconazole resistance.

Indexed as

adherencebiofilmCandida albicanshyphal formationstepwise acquired azole resistance in vivo

Identifiers

PMID36199677
PMCPMC9521591

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.