Evidence map›Paper›PMID 36199664›Full record

ArticleFrontiers in chemistry2022

Silk peptide-hyaluronic acid based nanogels for the enhancement of the topical administration of curcumin.

Jiangxiu Niu, Ming Yuan, Yao Liu, Liye Wang, Zigui Tang, Yihan Wang, Yueheng Qi, Yansong Zhang, Huiyuan Ya, Yanli Fan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiangxiu NiuCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Ming YuanCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Yao LiuCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Liye WangCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Zigui TangDepartment of Pharmacy, Henan Medical College, Zhengzhou, China.
Yihan WangCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Yueheng QiCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Yansong ZhangCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Huiyuan YaCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.
Yanli FanCollege of Food and Drug, Henan Functional Cosmetics Engineering and Technology Research Center, Luoyang Normal University, Luoyang, Henan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study focused on the development of Cur-loaded SOHA nanogels (Cur-SHNGs) to enhance the topical administration of Cur. The physiochemical properties of Cur-SHNGs were characterized. Results showed that the morphology of the Cur-SHNGs was spherical, the average size was 171.37 nm with a zeta potential of -13.23 mV. Skin permeation experiments were carried out using the diffusion cell systems. It was found that the skin retention of Cur-SHNGs was significantly improved since it showed the best retention value (0.66 ± 0.17 μg/cm

Indexed as

curcuminhyaluronic acidnanogelssilk peptidetopical administration

Identifiers

PMID36199664
PMCPMC9527322

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.