Evidence map›Paper›PMID 36199558›Full record

ArticleMaterials today. Bio2022

Injectable versatile liquid-solid transformation implants alliance checkpoint blockade for magnetothermal dynamic-immunotherapy.

Mengna Wang, Siyu Deng, Yijia Cao, Hang Zhou, Wei Wei, Kexiao Yu, Youde Cao, Bing Liang

Open access · goldAbstract read
In one paragraph

Article in Materials today. Bio, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Mengna WangDepartment of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
Siyu DengDepartment of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
Yijia CaoDepartment of Digestion, University-Town Hospital of Chongqing Medical University, Chongqing, 401331, PR China.
Hang ZhouInstitute of Ultrasound Imaging of Chongqing Medical University; The Second Affiliated Hospital of Chongqing Medical University, 76 Linjiang Road, Yuzhong District, Chongqing, 400010, PR China.
Wei WeiDepartment of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
Kexiao YuDepartment of Orthopedics, Chongqing Traditional Chinese Medicine Hospital, No. 6 Panxi Seventh Branch Road, Jiangbei District, Chongqing, 400021, PR China.
Youde CaoDepartment of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
Bing LiangDepartment of Pathology, College of Basic Medicine, Chongqing Medical University, Chongqing, 400016, PR China.
The Affiliated Yongchuan Hospital of Chongqing Medical University · CNDalian Medical University · CNChongqing Medical University · CNFirst People's Hospital of Chongqing · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing circulating energy loss, low reactive oxygen species (ROS) accumulation and poor immunogenicity of tumors make it difficult to induce sufficient immunogenic cell death (ICD) in the tumor immunosuppressive microenvironment (TIME), resulting in unsatisfactory immunotherapy efficacy. Furthermore, for highly malignant tumors, simply enhancing ICD is insufficient for exhaustively eliminating the tumor and inhibiting metastasis. Herein, we propose a unique magnetothermal-dynamic immunotherapy strategy based on liquid-solid transformation porous versatile implants (Fe

Indexed as

CTLA4 checkpoint blockadeFree radicalsImmunogenic cell deathLiquid-solid transformationMagnetothermal

Identifiers

PMID36199558
PMCPMC9527946
OpenAlexW4297499569

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.