ArticleScientific reports2022
Association of malnutrition with renal dysfunction and clinical outcome in patients with heart failure.
Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Natriuretic peptides and C-reactive protein in in heart failure and malnutrition: a systematic review and meta-analysis.ESC heart failure · 2024Pooled it
- Article
- Joint Associations of Residential Ambient PMNutrients · 2026Article
- Observational
- Anemia of Renal Tubular Damage and Mortality in the General Population: The Yamagata (Takahata) study.Internal medicine (Tokyo, Japan) · 2026Article
- Circulating CD19 B cell count, myocardial injury and clinical outcomes in patients with heart failure.ESC heart failure · 2025Article
- Malnutrition and Its Effect on Drug Pharmacokinetics: A Clinical Perspective.Clinical pharmacokinetics · 2025Review
- Sex modifies the association between malnutrition and chronic kidney disease in community-dwelling older adults in the United States.BMC geriatrics · 2025Article
- Predictive values of four nutritional indices for adverse outcomes in patients with hypertension.Clinical and experimental nephrology · 2025Article
- Malnutrition and Associated Factors Among Patients With Cirrhosis at a Tertiary Care Center in Addis Ababa Ethiopia: An Ordinal Logistic Regression Analysis.JGH open : an open access journal of gastroenterology and hepatology · 2025Article
- The Effect of Malnutrition, Inflammatory Biomarkers, and Stress-Induced Hyperglycemia on the Glomerular Filtration Rate in Renal Dysfunction.International journal of general medicine · 2025Article
- Association of prognostic nutritional index with all-cause mortality and cardiovascular mortality: a nationwide population-based cohort study.Frontiers in nutrition · 2025Article
- Factors Influencing Malnutrition in Patients with Heart Failure: A Scoping Review Based on the Biopsychosocial Model.Risk management and healthcare policy · 2025Review
- Association between controlling nutritional status score and chronic kidney disease in diabetic patients: a cross-sectional study based on the National Health and Nutrition Examination Survey.International urology and nephrology · 2024Article
- Article
- A Nomogram Incorporating Inflammation and Nutrition Indexes for Predicting Outcomes in Patients with Acute Coronary Syndrome and Chronic Kidney Disease.Journal of inflammation research · 2024Article
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Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malnutrition, glomerular damage (GD), and renal tubular damage (RTD) are common morbidities associated with poor clinical outcomes in heart failure (HF) patients. However, the association between malnutrition and renal dysfunction and its impact on clinical outcomes in HF patients have not yet been fully elucidated. We assessed the nutritional status and renal function of 1061 consecutive HF patients. Malnutrition, GD, and RTD were defined as a controlling nutritional status (CONUT) score of ≥ 5, reduced eGFR or microalbuminuria, and levels of N-acetyl-beta-D-glucosamidase of > 14.2 U/gCr according to previous reports, respectively. Patients with RTD had a higher CONUT score and a lower prognostic nutritional index and geriatric nutritional risk index than those without. Multivariate logistic analysis demonstrated that RTD, but not GD, was significantly associated with malnutrition. There were 360 cardiac events during the median follow-up period of 688 days. Multivariate Cox proportional hazard regression analysis demonstrated that comorbid malnutrition and renal dysfunction, rather than simple malnutrition, were significantly associated with cardiac events in HF patients. We found a close relationship between malnutrition and renal dysfunction in HF patients. Comorbid malnutrition and renal dysfunction were risk factors for cardiac events in HF patients, suggesting the importance of managing and treating these.
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