ArticleNature2022
SARS-CoV-2 disrupts host epigenetic regulation via histone mimicry.
Erratum issuedOpen access · bronzeAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 86 papers.
0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
14.6field-weighted citation impact, top 1% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
86 citing papers in PubMed, 146 citations in OpenAlex.
- Review
- From viral epigenetic reprogramming to neuroinflammation: Mechanisms driving neurodegeneration.Journal of neurovirology · 2026Review
- The cell with many faces: lung macrophage plasticity and function in response to environmental and pathogenic insults.Physiological reviews · 2026Review
- Unraveling the layers of epigenetic control in respiratory antiviral defense.Journal of virology · 2026Review
- Redundant and distinct mechanisms suppress innate immune activation during SARS-CoV-2 infection.PLoS biology · 2026Article
- Targeting Endothelial KDM5A to Attenuate Aging and Ameliorate Age-Associated Metabolic Abnormalities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- SARS-CoV-2 ORF8: an accessory protein at the interface of immune evasion and inflammation.Frontiers in immunology · 2026Review
- Functional Genomic Evidence for Candidate Small Viral RNA-Mediated Epigenetic Interference in SARS-CoV-1 and SARS-CoV-2.Computational and structural biotechnology journal · 2026Article
- Microbiota-driven epigenetic programming of local immunity.Frontiers in immunology · 2026Review
- Article
- SLUR(M)-py: a SLURM powered Pythonic pipeline for parallel processing of 3D (Epi)genomic profiles.Epigenomics · 2025Article
- Article
- COVID-19 Hijacking of the Host Epigenome: Mechanisms, Biomarkers and Long-Term Consequences.International journal of molecular sciences · 2025Review
- Human Coronavirus-229E Hijacks Key Host-Cell RNA-Processing Complexes for Replication.Journal of proteome research · 2025Article
- Aere perennius: how chromatin fidelity is maintained and lost in disease.NAR molecular medicine · 2025Review
- Targeting G9a-miScience · 2025Article
- The Recurring Loss of ORF8 Secretion in Dominant SARS-CoV-2 Variants.International journal of molecular sciences · 2025Article
- Differentially expressed ncRNAs as key regulators in infection of human bronchial epithelial cells by the SARS-CoV-2 Delta variant.Molecular therapy. Nucleic acids · 2025Article
- Beyond the Pandemic Era: Recent Advances and Efficacy of SARS-CoV-2 Vaccines Against Emerging Variants of Concern.Vaccines · 2025Review
- Nuclear warfare: pathogen manipulation of the nuclear pore complex and nuclear functions.mBio · 2025Review
26 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
- Erratum issued
Authors and funding
25 authors at 4 institutions in 1 country.
John KeeDepartment of Genetics at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Samuel Thudium *Department of Genetics at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-6670-3970
David M Renner *Department of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-0548-3876
Karl Glastad *Epigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Katherine PalozolaDepartment of Genetics at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Zhen ZhangEpigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Yize LiDepartment of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-1721-741X
Yemin LanEpigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Joseph CesareEpigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-5569-1422
Andrey PoleshkoDepartment of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-6656-2941
Anna A KiselevaDepartment of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-8720-5062
Rachel TruittDepartment of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Fabian L Cardenas-DiazDepartment of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Xianwen ZhangDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.
Xuping XieDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.ORCID http://orcid.org/0000-0003-0918-016X
Darrell N KottonCenter for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA, USA.ORCID http://orcid.org/0000-0002-9604-8476
Konstantinos D AlysandratosCenter for Regenerative Medicine, Boston University and Boston Medical Center, Boston, MA, USA.
Jonathan A EpsteinDepartment of Cell and Developmental Biology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Pei-Yong ShiDepartment of Biochemistry and Molecular Biology, University of Texas Medical Branch, Galveston, TX, USA.ORCID http://orcid.org/0000-0001-5553-1616
Wenli YangDepartment of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-1873-2336
Edward MorriseyDepartment of Medicine at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Benjamin A GarciaEpigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Shelley L BergerEpigenetics Institute at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-5398-4400
Susan R WeissDepartment of Microbiology at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.
Erica KorbDepartment of Genetics at the Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA. ekorb@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-7064-8123
University of Pennsylvania · USThe University of Texas Medical Branch at Galveston · USBoston University · USCalifornia Institute for Regenerative Medicine · US
Funding
Virology CoreU19AI171413 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI SARKO, CHRISTOPHER · 2022 to 2023
$75.0MShared Resources Core 2: Quantitative Proteomics CoreP01CA196539 · NCI · ROCKEFELLER UNIVERSITY · PI MUIR, TOM · 2015 to 2024
$17.6MWest African Center for Emerging Infectious DiseasesU01AI151801 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI Robert W Cross, Scott C Weaver · 2020 to 2026
$10.1MCardiac lineage determination and nuclear architectureR35HL140018 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI EPSTEIN, JONATHAN A. · 2018 to 2024
$6.8MViral modulation of epitranscriptomic mechanismsR01AI118891 · NIAID · WASHINGTON UNIVERSITY · PI GARCIA, BENJAMIN A, WEITZMAN, MATTHEW D. · 2015 to 2025
$5.4MMERS coronavirus: antagonism of double-stranded RNA induced host response by accessory proteinsR01AI140442 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI Susan R Weiss · 2018 to 2026
$5.1MTraining in Emerging Infectious DiseasesT32AI055400 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHERRY, SARA, HENSLEY, SCOTT ERIC · 2003 to 2022
$4.4MA National iPS Cell Network with Deep Phenotyping for Translational ResearchU01TR001810 · NCATS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI GILAD, YOAV, KOTTON, DARRELL N. · 2016 to 2020
$4.4MQuantitative mass spectrometry for comprehending epigenetic mechanisms in a new underlying neurological developmental disorderR01HD106051 · NICHD · WASHINGTON UNIVERSITY · PI Benjamin A Garcia · 2022 to 2026
$2.6MThe epigenetic encoding of learning and memoryDP2MH129985 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI KORB, ERICA MEGAN · 2021 to 2024
$2.4MThe Histone Code of Neuronal Function and DysfunctionR00MH111836 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI KORB, ERICA MEGAN · 2019 to 2021
$745kNCATS NIH HHS U01 TR001810NCI NIH HHS P01 CA196539NHLBI NIH HHS R35 HL140018NIAID NIH HHS HHSN272201600013CNIAID NIH HHS R01 AI118891NIAID NIH HHS R01 AI140442NIAID NIH HHS T32 AI055400NIAID NIH HHS U01 AI151801NIAID NIH HHS U19 AI171413NICHD NIH HHS R01 HD106051NIMH NIH HHS DP2 MH129985NIMH NIH HHS R00 MH111836
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged at the end of 2019 and caused the devastating global pandemic of coronavirus disease 2019 (COVID-19), in part because of its ability to effectively suppress host cell responses
Indexed as
COVID-19Epigenesis, GeneticHistonesHost Microbial InteractionsMolecular MimicrySARS-CoV-2Viral ProteinsChromatinChromatin Assembly and DisassemblyEpigenomeHumansChromatinHistonesORF8 protein, SARS-CoV-2Viral Proteins
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.