ArticleNature communications2022
Aschoff's rule on circadian rhythms orchestrated by blue light sensor CRY2 and clock component PRR9.
Article in Nature communications, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 25 citations in OpenAlex.
- Light at the heart of time: How photoreceptors entrain the circadian clock.Plant communications · 2026Review
- Genome-wide identification of the PIF gene family in broomcorn millet (Panicum miliaceum) highlights PmPIF5 as a candidate regulator of photoperiod responses.BMC plant biology · 2026Article
- Circadian oscillations in chromatin accessibility systematically orchestrate rhythmic gene transcription in soybean.The Plant cell · 2026Article
- A wireless leaf movement sensor system for early detection of abiotic stresses in Zea mays L.Plant methods · 2025Article
- Temperature compensation of the Arabidopsis circadian clock.Npj biological timing and sleep · 2025Review
- PhenoGazer: A high-throughput phenotyping system to track plant stress responses using hyperspectral reflectance, nighttime chlorophyll fluorescence and RGB imaging in controlled environments.Plant phenomics (Washington, D.C.) · 2025Article
- Complex Signaling Networks Underlying Blue-Light-Mediated Floral Transition in Plants.Plants (Basel, Switzerland) · 2025Review
- Spatiotemporal bifurcation of HY5-mediated blue-light signaling regulates wood development during secondary growth.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Characterization of the Cannabis sativa glandular trichome epigenome.BMC plant biology · 2024Article
- Cold-induced degradation of core clock proteins implements temperature compensation in theScience advances · 2024Article
- Light signaling in plants-a selective history.Plant physiology · 2024Review
- Light quality-dependent roles of REVEILLE proteins in the circadian system.Plant direct · 2024Article
- Photosynthetic adaptation strategies in peppers under continuous lighting: insights into photosystem protection.Frontiers in plant science · 2024Article
- The circadian clock of the bacteriumScience advances · 2023Article
- Blue light exposure-dependent improvement in robustness of circadian rest-activity rhythm in aged rats.PloS one · 2023Article
- Phytochromes and Their Role in Diurnal Variations of ROS Metabolism and Plant Proteome.International journal of molecular sciences · 2022Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Circadian pace is modulated by light intensity, known as the Aschoff's rule, with largely unrevealed mechanisms. Here we report that photoreceptor CRY2 mediates blue light input to the circadian clock by directly interacting with clock core component PRR9 in blue light dependent manner. This physical interaction dually blocks the accessibility of PRR9 protein to its co-repressor TPL/TPRs and the resulting kinase PPKs. Notably, phosphorylation of PRR9 by PPKs is critical for its DNA binding and repressive activity, hence to ensure proper circadian speed. Given the labile nature of CRY2 in strong blue light, our findings provide a mechanistic explanation for Aschoff's rule in plants, i.e., blue light triggers CRY2 turnover in proportional to its intensity, which accordingly releasing PRR9 to fine tune circadian speed. Our findings not only reveal a network mediating light input into the circadian clock, but also unmask a mechanism by which the Arabidopsis circadian clock senses light intensity.
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