SynthesisEuropean respiratory review : an official journal of the European Respiratory Society2022
Prognostic value of echocardiography-derived right ventricular dysfunction in haemodynamically stable pulmonary embolism: a systematic review and meta-analysis.
Synthesis in European respiratory review : an official journal of the European Respiratory Society, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 30 citations in OpenAlex.
- Prognostic impact of the e-TAPSE ratio in intermediate-high risk pulmonary embolism patients.The international journal of cardiovascular imaging · 2024Trial
- The diagnostic accuracy of left ventricular ejection fraction assessment between visual and artificial intelligence-based algorithms on bedside ultrasound.Cardiovascular ultrasound · 2026Article
- Initial management of intermediate- and high-risk pulmonary embolism.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2026Review
- Optimizing sPESI with heart rate threshold adjustments for risk stratification in acute pulmonary embolism: A retrospective cohort study.Vascular medicine (London, England) · 2026Article
- Safety and efficacy of low-dose versus high-dose alteplase for pulmonary embolism: a retrospective study from MIMIC-IV.Journal of thoracic disease · 2026Article
- Role of catheter-based interventions in treating pulmonary embolism.World journal of cardiology · 2025Review
- Acute Apical Sparing Strain Pattern of the Right Ventricle in Pulmonary Embolism: A Speckle-Tracking McConnell's Sign Equivalent.CASE (Philadelphia, Pa.) · 2025Article
- Coronary artery stenosis associated with right ventricular dysfunction in acute pulmonary embolism: A case-control study.Chinese medical journal · 2025Article
- Endovascular management of intermediate-risk pulmonary embolism: evidence, outstanding questions, drivers of utilization, and the horizon.European heart journal open · 2025Review
- Role of Transcatheter Treatment in Intermediate-to High-risk Pulmonary Embolism.Interventional cardiology (London, England) · 2025Review
- Prognostic values of right ventricular echocardiography functional parameters for mortality prediction in precapillary pulmonary hypertension: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2024Review
- Low Stroke Volume Predicts Deterioration in Intermediate-Risk Pulmonary Embolism: Prospective Study.The western journal of emergency medicine · 2024Article
- The role of echocardiography in pulmonary embolism for the prediction of in-hospital mortality: a retrospective study.Journal of ultrasound · 2024Article
- Evaluation of AT in acute pulmonary embolism with pleural effusion.Biomarkers in medicine · 2024Article
- Predictive value of reduced pulmonary arterial elasticity in acute pulmonary embolism for right ventricular dysfunction.Journal of thrombosis and thrombolysis · 2023Article
- Bilateral Emboli and Highest Heart Rate Predict Hospitalization of Emergency Department Patients With Acute, Low-Risk Pulmonary Embolism.Annals of emergency medicine · 2023Article
- Prevalence of long-term right ventricular dysfunction after acute pulmonary embolism: a systematic review and meta-analysis.EClinicalMedicine · 2023Article
- Low concordance between CTPA and echocardiography in identification of right ventricular strain in PERT patients with acute pulmonary embolism.Emergency radiology · 2023Article
- Prognostic role of different findings at echocardiography in acute pulmonary embolism: a critical review and meta-analysis.ERJ open research · 2023Article
- Baseline Echocardiographic Predictors of Outcomes in Low-to-intermediate Risk Acute Pulmonary Embolism and Integration with Electrocardiographic Findings: A Systematic Review and Meta-analysis.Journal of cardiovascular echographyArticle
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe sought to determine the prognostic value of transthoracic echocardiography (TTE)-derived right ventricular dysfunction (RVD) in haemodynamically stable and intermediate-risk patients with acute pulmonary embolism (PE), evaluate continuous RVD parameters, and assess the literature quality.
methodsWe searched MEDLINE, Embase and the Cochrane Central Register of Controlled Trials for studies assessing TTE-derived RVD in haemodynamically stable PE that reported in-hospital adverse events within 30 days. We determined pooled odds ratios (ORs) using a random-effects model, created funnel plots, evaluated the Newcastle-Ottawa scale and performed Grading of Recommendations, Assessment, Development and Evaluation.
resultsBased on 55 studies (17 090 patients, 37.8% RVD), RVD was associated with combined adverse events (AEs) (OR 3.29, 95% confidence interval (CI) 2.59-4.18), mortality (OR 2.00, CI 1.66-2.40) and PE-related mortality (OR 4.01, CI 2.79-5.78). In intermediate-risk patients, RVD was associated with AEs (OR 1.99, CI 1.17-3.37) and PE-related mortality (OR 6.16, CI 1.33-28.40), but not mortality (OR 1.63, CI 0.76-3.48). Continuous RVD parameters provide a greater spectrum of risk compared to categorical RVD. We identified publication bias, poor methodological quality in 34/55 studies and overall low certainty of evidence.
conclusionsRVD is frequent in PE and associated with adverse outcomes. However, data quality and publication bias are limitations of existing evidence.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.