Evidence map›Paper›PMID 36198043›Full record

ArticleMagnetic resonance in medicine2023

Contrast-optimal simultaneous multi-slice bSSFP cine cardiac imaging at 0.55 T.

Ye Tian, Sophia X Cui, Yongwan Lim, Nam G Lee, Ziwei Zhao, Krishna S Nayak

Open access · hybridAbstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Society for Cardiovascular Magnetic Resonance recommendations toward environmentally sustainable cardiovascular magnetic resonance.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Feasibility of tagged MRI at 0.55 T.Magnetic resonance in medicine · 2026
    Article
  8. Article
  9. Simultaneous multi-slice cardiac real-time MRI at 0.55T.Magnetic resonance in medicine · 2025
    Article
  10. Article
  11. Review
  12. Feasibility of fetal cardiac function and anatomy assessment by real-time spiral balanced steady-state free precession magnetic resonance imaging at 0.55T.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2025
    Article
  13. Review
  14. Review
  15. Cardiac MRI at Low Field Strengths.Journal of magnetic resonance imaging : JMRI · 2024
    Review
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ye TianMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0002-8559-4404
Sophia X CuiSiemens Medical Solutions USA, Los Angeles, California, USA.
Yongwan LimMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-0070-0034
Nam G LeeDepartment of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-5462-1492
Ziwei ZhaoMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0003-0281-1141
Krishna S NayakMing Hsieh Department of Electrical and Computer Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California, USA.ORCID 0000-0001-5735-3550
University of Southern California · USSiemens Healthcare (United States) · US

Funding

Novel Myocardial Perfusion Stress Test using Arterial Spin LabelingR01HL130494 · NHLBI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI NAYAK, KRISHNA S · 2016 to 2019
$1.7M
NHLBI NIH HHS R01 HL130494
6 · The paper itself

Abstract

purposeTo determine if contemporary 0.55 T MRI supports the use of contrast-optimal flip angles (FA) for simultaneous multi-slice (SMS) balanced SSFP (bSSFP) cardiac function assessment, which is impractical at conventional field strengths because of excessive SAR and/or banding artifacts.

methodsBlipped-CAIPI bSSFP was combined with spiral sampling for ventricular function assessment at 0.55 T. Cine movies with single band and SMS factors of 2 and 3 (SMS 2 and 3), and FA ranging from 60° to 160°, were acquired in seven healthy volunteers. Left ventricular blood and myocardial signal intensity (SI) normalized by background noise and blood-myocardium contrast were measured and compared across acquisition settings.

resultsMyocardial SI was slightly higher in single band than in SMS and decreased with an increasing FA. Blood SI increased as the FA increased for single band, and increment was small for FA ≥120°. Blood SI for SMS 2 and 3 increased with an increasing FA up to ∼100°. Blood-myocardium contrast increased with an increasing FA for single band, peaked at FA = 160° (systole: 28.43, diastole: 29.15), attributed mainly to reduced myocardial SI when FA ≥120°. For SMS 2, contrast peaked at 120° (systole: 21.43, diastole: 19.85). For SMS 3, contrast peaked at 120° in systole (16.62) and 100° in diastole (19.04).

conclusionsContemporary 0.55 T MR scanners equipped with high-performance gradient systems allow the use of contrast-optimal FA for SMS accelerated bSSFP cine examinations without compromising image quality. The contrast-optimal FA was found to be 140° to 160° for single band and 100° to 120° for SMS 2 and 3.

Indexed as

HeartImage Interpretation, Computer-AssistedHeart VentriclesHumansMagnetic Resonance ImagingMagnetic Resonance Imaging, CineMyocardium0.55 Tbalanced steady-state free precessionblood-myocardium contrastcardiac functionsimultaneous multi-slice

Identifiers

PMID36198043
PMCPMC9712243
OpenAlexW4302027486

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.