Evidence map›Paper›PMID 36198001›Full record

ArticleMagnetic resonance in medicine2023

Self-calibrated through-time spiral GRAPPA for real-time, free-breathing evaluation of left ventricular function.

Dominique Franson, James Ahad, Yuchi Liu, Alexander Fyrdahl, William Truesdell, Jesse Hamilton, Nicole Seiberlich

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Accelerated Abdominal MRI: A Review of Current Methods and Applications.Journal of magnetic resonance imaging : JMRI · 2025
    Review
  2. The future of CMR: All-in-one vs. real-time CMR (Part 2).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Dominique FransonDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0002-9870-3147
James AhadDepartment of Biomedical Engineering, Case Western Reserve University, Cleveland, Ohio, USA.ORCID 0000-0003-2415-2343
Yuchi LiuDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-3533-1697
Alexander FyrdahlDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0003-0237-7699
William TruesdellDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.
Jesse HamiltonDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-4463-481X
Nicole SeiberlichDepartment of Radiology, University of Michigan, Ann Arbor, Michigan, USA.

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM007250 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI HUANG, ALEX YEE-CHEN · 1985 to 2023
$33.4M
Medical Scientist Training Program at Case Western Reserve UniversityT32GM152319 · NIGMS · CASE WESTERN RESERVE UNIVERSITY · PI Heather Broihier, Alex Yee-Chen Huang · 2024 to 2026
$5.1M
Magnetic Resonance Imaging Guided Robotic Catheter System for Left Atrial Appendage Occlusion ProceduresR01HL163991 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI BEZERRA, HIRAM, CAVUSOGLU, M. CENK · 2022 to 2025
$3.7M
3D Cine Magnetic Resonance Fingerprinting for Rapid Phenotyping of CardiomyopathyR01HL163030 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI JESSE Ian HAMILTON, Imran Rashid · 2022 to 2026
$3.2M
Real-Time MRI Guided Robotic Catheter System for Atrial Fibrillation AblationR01HL153034 · NHLBI · CASE WESTERN RESERVE UNIVERSITY · PI CAVUSOGLU, M. CENK, GRISWOLD, MARK · 2020 to 2023
$2.7M
Development of Real-time MR imaging and Visualization System to Improve MR-guided Prostate BiopsyF30CA239355 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI AHAD, JAMES NOLAN · 2020 to 2022
$153k
NCI NIH HHS F30 CA239355NHLBI NIH HHS R01 HL153034NHLBI NIH HHS R01 HL163030NHLBI NIH HHS R01 HL163991NIGMS NIH HHS T32 GM007250NIGMS NIH HHS T32 GM152319NIH HHS F30CA239355NIH HHS R01HL153034NIH HHS T32GM07250
6 · The paper itself

Abstract

purposeThrough-time spiral GRAPPA is a real-time imaging technique that enables ungated, free-breathing evaluation of the left ventricle. However, it requires a separate fully-sampled calibration scan to calculate GRAPPA weights. A self-calibrated through-time spiral GRAPPA method is proposed that uses a specially designed spiral trajectory with interleaved arm ordering such that consecutive undersampled frames can be merged to form calibration data, eliminating the separate fully-sampled acquisition. THEORY AND

methodsThe proposed method considers the time needed to acquire data at all points in a GRAPPA calibration kernel when using interleaved arm ordering. Using this metric, simulations were performed to design a spiral trajectory for self-calibrated GRAPPA. Data were acquired in healthy volunteers using the proposed method and a comparison electrocardiogram-gated and breath-held cine scan. Left ventricular functional values and image quality are compared.

resultsA 12-arm spiral trajectory was designed with a temporal resolution of 32.72 ms/cardiac phase with an acceleration factor of 3. Functional values calculated using the proposed method and the gold-standard method were not statistically significantly different (paired t-test, p < 0.05). Image quality ratings were lower for the proposed method, with statistically significantly different ratings (Wilcoxon signed rank test, p < 0.05) for two of five image quality aspects rated (level of artifact, blood-myocardium contrast).

conclusionsA self-calibrated through-time spiral GRAPPA reconstruction can enable ungated, free-breathing evaluation of the left ventricle in 71 s. Functional values are equivalent to a gold-standard cine technique, although some aspects of image quality may be inferior due to the real-time nature of the data collection.

Indexed as

RespirationVentricular Function, LeftAlgorithmsArtifactsBreath HoldingHeartHumansImage Processing, Computer-AssistedMagnetic Resonance Imaging, CineReproducibility of Resultscardiovascular magnetic resonanceGRAPPAnon-Cartesianparallel imagingreal-timespiral

Identifiers

PMID36198001
PMCPMC10092570

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.