Evidence map›Paper›PMID 36197974›Full record

ArticleScience advances2022

The linker domain of the initiator DnaA contributes to its ATP binding and membrane association in

Yanqi Hou, Pankaj Kumar, Monika Aggarwal, Farzad Sarkari, Karen M Wolcott, Dhruba K Chattoraj, Elliott Crooke, Rahul Saxena

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Phage Mu enlists the β-sliding clamp for late gene transcription.Proceedings of the National Academy of Sciences of the United States of America · 2026
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  10. IHF and Fis asInternational journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yanqi HouDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0003-2170-339X
Pankaj KumarCenter for Tuberculosis Research, Department of Medicine, Johns Hopkins University, Baltimore, MD 21287, USA.ORCID 0000-0001-9163-3273
Monika AggarwalLombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20007, USA.
Farzad SarkariDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA.
Karen M WolcottLaboratory of Genome Integrity, Flow Cytometry Core Facility, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Dhruba K ChattorajBasic Research Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Elliott CrookeDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0003-4867-8155
Rahul SaxenaDepartment of Biochemistry and Molecular and Cellular Biology, Georgetown University Medical Center, Washington, DC 20007, USA.ORCID 0000-0003-4252-1368
Georgetown University · USNational Institutes of Health · USJohns Hopkins University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

DnaA, the initiator of

Indexed as

DNA-Binding ProteinsEscherichia coliAdenosineAdenosine TriphosphatasesAdenosine TriphosphateBacterial ProteinsDNA ReplicationMembrane LipidsReplication OriginAdenosineAdenosine TriphosphatasesAdenosine TriphosphateBacterial ProteinsDNA-Binding ProteinsMembrane Lipids

Identifiers

PMID36197974
PMCPMC9534497
OpenAlexW4302282248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.