Evidence map›Paper›PMID 36197801›Full record

ArticleACS chemical neuroscience2022

Identification of CB1 Ligands among Drugs, Phytochemicals and Natural-Like Compounds: Virtual Screening and In Vitro Verification.

Adam Stasiulewicz, Anna Lesniak, Piotr Setny, Magdalena Bujalska-Zadrożny, Joanna I Sulkowska

Open access · hybridAbstract read
In one paragraph

Article in ACS chemical neuroscience, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Adam StasiulewiczDepartment of Drug Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.ORCID 0000-0003-3346-5579
Anna LesniakDepartment of Pharmacodynamics, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Piotr SetnyCentre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.ORCID 0000-0002-0769-0943
Magdalena Bujalska-ZadrożnyDepartment of Pharmacodynamics, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland.
Joanna I SulkowskaCentre of New Technologies, University of Warsaw, Banacha 2c, 02-097 Warsaw, Poland.ORCID 0000-0003-2452-0724
Medical University of Warsaw · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cannabinoid receptor type 1 (CB1) is an important modulator of many key physiological functions and thus a compelling molecular target. However, safe CB1 targeting is a non-trivial task. In recent years, there has been a surge of data indicating that drugs successfully used in the clinic for years (e.g. paracetamol) show CB1 activity. Moreover, there is a lot of promise in finding CB1 ligands in plants other than

Indexed as

AcetaminophenEndocannabinoidsLigandsPhytochemicalsReceptor, Cannabinoid, CB1Receptors, CannabinoidTravoprostAcetaminophenEndocannabinoidsLigandsPhytochemicalsReceptor, Cannabinoid, CB1Receptors, CannabinoidTravoprostcannabinoid receptordockingginkgetinphytocannabinoidsQSARtravoprost

Identifiers

PMID36197801
PMCPMC9585589
OpenAlexW4302028454

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.