Evidence map›Paper›PMID 36197564›Full record

ArticleTechniques in coloproctology2022

Predictive factors for functional failure of ventral mesh rectopexy in the treatment of rectal prolapse and obstructed defecation.

S Solari, J Martellucci, S Ascanelli, A Sturiale, A Annicchiarico, B Fabiani, P Prosperi, P Carcoforo, G Naldini

Open access · hybridAbstract read
In one paragraph

Article in Techniques in coloproctology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. 2025 Delphi consensus on robotic ventral mesh rectopexy.International journal of colorectal disease · 2025
    Guideline
  2. Pooled it
  3. Article
  4. Beyond stapled transanal rectal resectionWorld journal of gastrointestinal surgery · 2026
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

S SolariDepartment of Medical Science, University of Ferrara, Ferrara, Italy. dr.stefano.solari@gmail.com.ORCID 0000-0001-7719-7786
J MartellucciEmergency Surgery, Careggi University Hospital, Florence, Italy.
S AscanelliDepartment of Medical Science, University of Ferrara, Ferrara, Italy.
A SturialeProctology and Pelvic Floor Clinical Center, University Hospital of Pisa, Pisa, Italy.
A AnnicchiaricoDepartment of Medicine and Surgery, University of Parma, Parma, Italy.
B FabianiProctology and Pelvic Floor Clinical Center, University Hospital of Pisa, Pisa, Italy.
P ProsperiEmergency Surgery, Careggi University Hospital, Florence, Italy.
P CarcoforoDepartment of Medical Science, University of Ferrara, Ferrara, Italy.
G NaldiniProctology and Pelvic Floor Clinical Center, University Hospital of Pisa, Pisa, Italy.
Azienda Ospedaliera Universitaria Pisana · ITUniversity of Ferrara · ITAzienda Ospedaliero-Universitaria Careggi · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVentral mesh rectopexy (VMR) is widely accepted for the treatment of rectal prolapse or obstructed defecation. However, despite good anatomical results, the improvement of functional symptoms (constipation or incontinence) cannot always be obtained and in some cases these symptoms may even worsen. The aim of the present study was to identify possible predictors of functional failure after VMR.

methodsData of all consecutive patients who had VMR for the treatment of rectal prolapse and/or obstructed defecation between January 2017 and December 2020 in three different pelvic floor surgical centres in Italy were analysed to identify possible predictors of functional failure, intended as persistence, worsening or new onset of constipation or faecal incontinence. Symptom severity was assessed pre- and postoperatively with the Wexner Constipation score and Obstructed Defecation Syndrome score. Quality of life was assessed, also before and after treatment, with the Patients Assessment of Constipation Quality of Life questionnaire, the Pelvic Floor Disability Index and the Pelvic Floor Impact Questionnaire. Faecal incontinence was evaluated with the Cleveland Clinic Incontinence Score. The functional outcomes before and after surgery were compared.

resultsSixty-one patients were included (M:F ratio 3:60, median age 64 years [range 33-88 years]). Forty-two patients (68.9%) had obstructed defecation syndrome, 12(19.7%) had faecal incontinence and 7 patients (11.5%) had both. A statistically significant reduction between pre- and postoperative Obstructed Defecation Syndrome and Wexner scores was reported (p < 0.0001 in both cases). However, the postoperative presence of constipation occurred in 22 patients (36.1%) (this included 3 cases of new-onset constipation). The presence of redundant colon and the pre-existent constipation were associated with an increased risk of persistence of constipation postoperatively or new-onset constipation (p = 0.004 and p < 0.0001, respectively). The use of postoperative pelvic floor rehabilitation (p = 0.034) may reduce the risk of postoperative constipation.

conclusionsVMR is a safe and effective intervention for correcting the anatomical defect of rectal prolapse. The degree of prolapse, the presence of dolichocolon and pre-existing constipation are risk factors for the persistence or new onset of postoperative constipation. Postoperative rehabilitation treatment may reduce this risk.

Indexed as

Fecal IncontinenceLaparoscopyRectal ProlapseAdultAgedAged, 80 and overConstipationDefecationHumansMiddle AgedQuality of LifeRectumSurgical MeshTreatment OutcomeConstipationODSPelvic floorProctologyRectal prolapseVentral mesh rectopexy

Identifiers

PMID36197564
PMCPMC9637597
OpenAlexW4301595385

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.