Evidence map›Paper›PMID 36197548›Full record

ArticleJournal of clinical monitoring and computing2023

Pressure response to fluid challenge administration in hypotensive surgical patients: a post-hoc pharmacodynamic analysis of five datasets.

Antonio Messina, Davide Colombo, Giulia Lionetti, Lorenzo Calabrò, Katerina Negri, Chiara Robba, Gianmaria Cammarota, Elena Costantini, Maurizio Cecconi

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Article in Journal of clinical monitoring and computing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Antonio MessinaIRCCS Humanitas Research Hospital, Rozzano (MI), Italy. antonio.messina@humanitas.it.
Davide ColomboAnesthesia and Intensive Care Medicine, Ospedale Ss. Trinità, Borgomanero, Italy.
Giulia LionettiIRCCS Humanitas Research Hospital, Rozzano (MI), Italy.
Lorenzo CalabròIRCCS Humanitas Research Hospital, Rozzano (MI), Italy.
Katerina NegriDepartment of Anesthesia and Intensive Care, Università degli studi di Milano, Milan, Italy.
Chiara RobbaAnesthesia and Intensive Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neuroscience, Genoa, Italy.
Gianmaria CammarotaDipartimento di Medicina e Chirurgia, Università di Perugia, Perugia, Italy.
Elena CostantiniIRCCS Humanitas Research Hospital, Rozzano (MI), Italy.
Maurizio CecconiIRCCS Humanitas Research Hospital, Rozzano (MI), Italy.
IRCCS Humanitas Research Hospital · ITOspedale Policlinico San Martino · ITUniversity of Milan · ITUniversity of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study we evaluated the effect of fluid challenge (FC) administration in elective surgical patients with low or normal blood pressure. Secondarily, we appraised the pharmacodynamic effect of FC in normotensive and hypotensive patients. We assessed five merged datasets of patients with a baseline mean arterial pressure (MAP) above or below 65 mmHg and assessed the changes of systolic, diastolic, mean and dicrotic arterial pressures, dynamic indexes of fluid responsiveness and arterial elastance over a 10-min infusion. The hemodynamic effect was assessed by considering the net area under the curve (AUC), the maximal percentage difference from baseline (d

Indexed as

Fluid TherapyHypotensionArterial PressureBlood PressureHemodynamicsHumansStroke VolumeFluid challengeFluid responsivenessFluid therapyHaemodynamicsPharmacodynamic

Identifiers

PMID36197548
OpenAlexW4301586637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.