Evidence map›Paper›PMID 36197116›Full record

ArticleAntimicrobial agents and chemotherapy2022

New

Sebastian G Wicha, Annabelle Walz, Mohammed H Cherkaoui-Rbati, Nils Bundgaard, Karsten Kuritz, Christin Gumpp, Nathalie Gobeau, Jörg Möhrle, Matthias Rottmann, Claudia Demarta-Gatsi

Open access · hybridAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Selective targeting ofAntimicrobial agents and chemotherapy · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. IncompleteFrontiers in cellular and infection microbiology · 2024
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Sebastian G WichaDepartment of Clinical Pharmacy, Institute of Pharmacy, University of Hamburg, Hamburg, Germany.
Annabelle WalzDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Mohammed H Cherkaoui-RbatiMedicines for Malaria Venturegrid.452605.0, Geneva, Switzerland.
Nils BundgaardIntiQuan GmbH, Basel, Switzerland.
Karsten KuritzIntiQuan GmbH, Basel, Switzerland.
Christin GumppDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Nathalie GobeauMedicines for Malaria Venturegrid.452605.0, Geneva, Switzerland.
Jörg MöhrleMedicines for Malaria Venturegrid.452605.0, Geneva, Switzerland.ORCID 0000-0002-0769-9649
Matthias RottmannDepartment of Medical Parasitology and Infection Biology, Swiss Tropical and Public Health Institute, Allschwil, Switzerland.
Claudia Demarta-GatsiMedicines for Malaria Venturegrid.452605.0, Geneva, Switzerland.ORCID 0000-0002-9610-2962
Medicines for Malaria Venture · CHSwiss Tropical and Public Health Institute · CHUniversität Hamburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development and spread of drug-resistant phenotypes substantially threaten malaria control efforts. Combination therapies have the potential to minimize the risk of resistance development but require intensive preclinical studies to determine optimal combination and dosing regimens. To support the selection of new combinations, we developed a novel

Indexed as

AntimalarialsMalariaMalaria, FalciparumParasitesAdamantaneAminoquinolinesAnimalsDrug CombinationsFerrous CompoundsHumansMetallocenesMicePeroxidesPlasmodium falciparumAdamantaneAminoquinolinesAntimalarialsartefenomelDrug CombinationsferroquineFerrous CompoundsMetallocenesPeroxidesdrug combinationsdrug-drug interactionsin vitro-in silico preclinical strategypharmacometric modelsPlasmodium

Identifiers

PMID36197116
PMCPMC9664866
OpenAlexW4302028357

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.