Evidence map›Paper›PMID 36196591›Full record

GuidelineUnited European gastroenterology journal2022

UEG and EAES rapid guideline: Update systematic review, network meta-analysis, CINeMA and GRADE assessment, and evidence-informed European recommendations on surgical management of GERD.

Sheraz Markar, Alexandros Andreou, Luigi Bonavina, Ivan D Florez, Bright Huo, Katerina-Maria Kontouli, Donald E Low, Dimitris Mavridis, Nick Maynard, Alan Moss and 7 more

Open access · greenAbstract readPractice GuidelineSystematic ReviewNetwork Meta-Analysis
In one paragraph

Guideline in United European gastroenterology journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 27 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Review
  4. Review
  5. Article
  6. Quality of clinical guidelines: It matters as it impacts patient care.United European gastroenterology journal · 2024
    Article
  7. The quality of outcome in anti-reflux surgery is multi-factorial.United European gastroenterology journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 17 institutions in 12 countries.

Sheraz MarkarNuffield Department of Surgery, University of Oxford, Oxford, UK.ORCID 0000-0002-4040-5681
Alexandros AndreouDepartment of Surgery, York Teaching Hospital NHS Foundation Trust, York, UK.
Luigi BonavinaDepartment of Biomedical Sciences for Health, Division of General and Foregut Surgery, IRCCS Policlinico San Donato, University of Milan, Milan, Italy.ORCID 0000-0002-4880-1670
Ivan D FlorezDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0002-0751-8932
Bright HuoFaculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada.ORCID 0000-0003-4999-4328
Katerina-Maria KontouliDepartment of Primary Education, School of Education University of Ioannina, Ioannina, Greece.
Donald E LowDepartment of Thoracic Surgery and Surgical Oncology, Virginia Mason Medical Center, Seattle, Washington, USA.
Dimitris MavridisDepartment of Primary Education, School of Education University of Ioannina, Ioannina, Greece.
Nick MaynardNuffield Department of Surgery, University of Oxford, Oxford, UK.
Alan MossAction Against Heartburn, London, UK.
Manuel PeraGastroesophageal Carcinogenesis Research Group, Hospital del Mar Medical Research Institute (IMIM), Barcelona, Spain.
Edoardo SavarinoDepartment of Surgery, Oncology and Gastroenterology, Gastroenterology Unit, University of Padua, Padua, Italy.
Peter SiersemaDepartment of Gastroenterology and Hepatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Daniel SifrimWingate Institute of Neurogastroenterology, Blizard Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.
David I WatsonFlinders University Discipline of Surgery, Flinders Medical Centre, Bedford Park, South Australia, Australia.
Giovanni ZaninottoDepartment of Surgery and Cancer, Imperial College London, London, UK.
Stavros A AntoniouEuropean University Cyprus, Nicosia, Cyprus.ORCID 0000-0002-4630-6748
Action Against Medical Accidents · GBDalhousie University · CADélégation Paris 5 · FREuropean University Cyprus · CYFlinders University · AUImperial College London · GBKarolinska Institutet · SEQueen Mary University of London · GBRadboud University Nijmegen · NLUniversidad de Antioquia · COUniversitat Autònoma de Barcelona · ESUniversity of Ioannina · GRUniversity of Milan · ITUniversity of Oxford · GBUniversity of Padua · ITVirginia Mason Medical Center · USYork Teaching Hospital NHS Foundation Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThere are several options for the surgical management of GERD in adults. Previous guidelines and systematic reviews have compared the effects of total fundoplication versus pooled effects of different techniques of partial fundoplication.

objectiveTo develop evidence-informed, trustworthy, pertinent recommendations on the use of total, posterior partial and anterior partial fundoplications for the management of GERD in adults.

methodsWe performed an update systematic review, network meta-analysis, and evidence appraisal using the GRADE and the Confidence in Network Meta-Analysis methodologies. An international, multidisciplinary panel of surgeons, gastroenterologists, and a patient representative reached unanimous consensus through an evidence-to-decision framework to select among multiple interventions, and a Delphi process to formulate the recommendation. The project was developed in an online authoring and publication platform (MAGICapp), and was overseen by an external auditor.

resultsWe suggest posterior partial fundoplication over total posterior or anterior 90° fundoplication in adult patients with GERD. We suggest anterior >90° fundoplication as an alternative, although relevant comparative evidence is limited (weak recommendation). The guideline, with recommendations, evidence summaries and decision aids in user friendly formats can also be accessed in MAGICapp: https://app.magicapp.org/#/guideline/j20X4n.

conclusionThis rapid guideline was developed in line with highest methodological standards and provides evidence-informed recommendations on the surgical management of GERD. It provides user-friendly decision aids to inform healthcare professionals' and patients' decision making.

Indexed as

Gastroesophageal RefluxGRADE ApproachHumansAGREE-SfundoplicationGERDguidelineNissenToupét

Identifiers

PMID36196591
PMCPMC9731663
OpenAlexW4302275437

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.