Evidence map›Paper›PMID 36196584›Full record

ArticleNeuropsychopharmacology reports2022

Association between functional recovery and medication adherence in schizophrenia.

Junpei Ishii, Fumitoshi Kodaka, Hisatsugu Miyata, Wataru Yamadera, Hikaru Seto, Hidejiro Higuchi, Yoshiaki Tsuruoka, Masahiro Shigeta

Open access · goldAbstract read
In one paragraph

Article in Neuropsychopharmacology reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Junpei IshiiDepartment of Psychiatry, Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0002-4895-4095
Fumitoshi KodakaDepartment of Psychiatry, Jikei University School of Medicine, Tokyo, Japan.ORCID 0000-0002-9296-5736
Hisatsugu MiyataDepartment of Psychiatry, Jikei University School of Medicine, Tokyo, Japan.
Wataru YamaderaDepartment of Psychiatry, Jikei University Katsushika Medical Center, Tokyo, Japan.
Hikaru SetoDepartment of Psychiatry, Sobu Hospital, Chiba, Japan.
Hidejiro HiguchiDepartment of Psychiatry, Sobu Hospital, Chiba, Japan.
Yoshiaki TsuruokaDepartment of Psychiatry, Otaki Hospital, Chiba, Japan.
Masahiro ShigetaDepartment of Psychiatry, Jikei University School of Medicine, Tokyo, Japan.
Jikei University School of Medicine · JPKatsushika Medical Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimMedication adherence is important for achieving functional recovery from schizophrenia and is commonly assessed using the Drug Attitude Inventory-30 (DAI-30). Subscales of the DAI-30, including "awareness of the need for medication," "awareness of the effects of psychiatric drugs," and "impression of medication," have been used to assess medication adherence. To determine which of these subscales are associated with the prognosis of schizophrenia, this study followed patients with schizophrenia to identify the prognosis and examine the subscales related to "recovery."

methodsIn total, 89 patients were recruited, 78 of whom were registered in the study. After assessing adherence using the DAI-30, Positive and Negative Syndrome Scale and Global Assessment of Functioning scores were assessed at 0 and 24 week to define the functional prognosis.

resultsAt the end of the 24-week follow-up period, 36% of patients showed recovery from schizophrenia. A comparison of subscales revealed that the score for "impression of medication" was significantly higher in the recovery than in the non-recovery group. Logistic regression analysis identified only the "impression of medication" score as being predictive of recovery.

conclusionThe results indicated that among the three DAI-30 subscales, "impression of medication" was the most closely associated with recovery in patients with schizophrenia.

Indexed as

Antipsychotic AgentsSchizophreniaHumansMedication AdherenceSchizophrenic PsychologySeverity of Illness IndexAntipsychotic Agentsfunctional recoverymedication adherenceprognosisschizophreniatrait anxiety

Identifiers

PMID36196584
PMCPMC9773647
OpenAlexW4302276454

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.