ArticleProceedings. Biological sciences2022
Higher phage virulence accelerates the evolution of host resistance.
Article in Proceedings. Biological sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
13 citing papers in PubMed.
- Host Range Breadth Correlates with Genic Diversity in Honeybee Phages.Genome biology and evolution · 2026Article
- Temperate bacteriophage induced inBiofilm · 2025Article
- Experimental Coevolution Reveals That Ralstonia pseudosolanacearum PhcA Contributes to the Infection of Filamentous Phage RSCq.Molecular plant pathology · 2025Article
- Article
- The intestinal environment potentiates bacteriophage adaptation in response to phenotypic resistance inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Warming During Different Life Stages has Distinct Impacts on Host Resistance Ecology and Evolution.Ecology letters · 2025Article
- "French Phage Network" annual conference: ninth meeting report.microLife · 2025Article
- Hard to jump: host shifts appear unlikely in a T4-like phage evolved in the lab.Frontiers in cellular and infection microbiology · 2025Article
- Review
- Phage-induced efflux down-regulation boosts antibiotic efficacy.PLoS pathogens · 2024Article
- Slow growing bacteria survive bacteriophage in isolation.ISME communications · 2023Article
- Ecology and Evolutionary Biology of Hindering Phage Therapy: The Phage Tolerance vs. Phage Resistance of Bacterial Biofilms.Antibiotics (Basel, Switzerland) · 2023Review
- Higher phage virulence accelerates the evolution of host resistance.Proceedings. Biological sciences · 2022Article
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogens vary strikingly in their virulence and the selection they impose on their hosts. While the evolution of different virulence levels is well studied, the evolution of host resistance in response to different virulence levels is less understood and, at present, mainly based on observations and theoretical predictions with few experimental tests. Increased virulence can increase selection for host resistance evolution if the benefits of avoiding infection outweigh resistance costs. To test this, we experimentally evolved the bacterium
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.