Evidence map›Paper›PMID 36196402›Full record

ArticlePeerJ2022

Evaluation of total immunoglobulin G and subclass antibodies in an enzyme-linked immunosorbent assay for serodiagnosis of human amebic liver abscess.

Penchom Janwan, Lakkhana Sadaow, Rutchanee Rodpai, Hiroshi Yamasaki, Vor Luvira, Wattana Sukeepaisarnjaroen, Amnat Kitkhuandee, Krisada Paonariang, Oranuch Sanpool, Patcharaporn Boonroumkaew and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Amebic liver abscess: An update.World journal of hepatology · 2024
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Penchom JanwanDepartment of Medical Technology, School of Allied Health Sciences, Walailak University, Nakhon Si Thammarat, Thailand.
Lakkhana SadaowDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Rutchanee RodpaiDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Hiroshi YamasakiDepartment of Parasitology, National Institute of Infectious Diseases, Tokyo, Japan.
Vor LuviraDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Wattana SukeepaisarnjaroenDepartment of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Amnat KitkhuandeeDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Krisada PaonariangDepartment of Surgery, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Oranuch SanpoolDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Patcharaporn BoonroumkaewDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Tongjit ThanchomnangMekong Health Science Research Institute, Khon Kaen University, Khon Kaen, Thailand.
Toshihiro MitaDepartment of Tropical Medicine and Parasitology, Juntendo University School of Medicine, Tokyo, Japan.
Pewpan M IntapanDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Wanchai MaleewongDepartment of Parasitology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.
Khon Kaen University · THJuntendo University · JPNational Institute of Infectious Diseases · JPWalailak University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Amebic liver abscess (ALA) caused by Methods: A serological ELISA-based test was performed to assess its diagnostic performance using a total of 330 serum samples from ALA patients ( Results: ELISA targeting the total IgG antibody to Conclusion: ELISA targeting IgG1 can provide valuable information to clinicians in differentiating ALA from other parasitic diseases, cancers, cirrhosis, and viral hepatitis. However, enzyme-conjugated anti-human total IgG is cheaper than anti-human IgG subclasses. Therefore, we suggest that total IgG-based ELISA is sufficient for the routine serodiagnosis of human ALA and possibly other clinical manifestations of invasive amebiasis.

Indexed as

Liver Abscess, AmebicAntibodies, ProtozoanEnzyme-Linked Immunosorbent AssayHumansImmunoglobulin GSerologic TestsAntibodies, ProtozoanImmunoglobulin GAmebic liver abscessEntamoeba histolyticaEnzyme-linked immunosorbent assayImmunoglobulin G subclassesSerodiagnosis

Identifiers

PMID36196402
PMCPMC9527022
OpenAlexW4298004306

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.