Evidence map›Paper›PMID 36196399›Full record

ReviewPeerJ2022

Macrophages play a key role in tissue repair and regeneration.

Yajie Yu, Zhongyu Yue, Mengli Xu, Meiling Zhang, Xue Shen, Zihan Ma, Juan Li, Xin Xie

Open access · goldAbstract readReview
In one paragraph

Review in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 69 papers.

0numbers the graph read from it
0cells of the map it votes in
69citing papers in PubMed
20.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

69 citing papers in PubMed, 99 citations in OpenAlex.

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  19. CD160Cellular & molecular immunology · 2026
    Article
  20. Bilayer gelatin-methacryloyl scaffold for pulp inflammation suppression and dentin-like tissue regeneration.Journal of controlled release : official journal of the Controlled Release Society · 2026
    Article

9 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yajie YuCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Zhongyu YueCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Mengli XuCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Meiling ZhangCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Xue ShenCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Zihan MaCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Juan LiCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Xin XieCollege of Life Science, Northwest University, Xi'an, Shaanxi, China.
Northwest University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tissue regeneration after body injury has always been a complex problem to resolve for mammals. In adult mammals, the repair process after tissue injury is often accompanied by continuous and extensive fibrosis, which leads to scars. This process has been shown to severely hinder regeneration. Macrophages, as widely distributed innate immune cells, not only play an important role in various pathological processes, but also participate in the repair process before tissue regeneration and coordinate the regeneration process after repair. This review will discuss the various forms and indispensability of macrophages involved in repair and regeneration, and how macrophages play a role in the repair and regeneration of different tissues.

Indexed as

MacrophagesWound HealingAnimalsCicatrixFibrosisMammalsCytokineMacrophagePolarizationRegenerationTissue repair

Identifiers

PMID36196399
PMCPMC9527023
OpenAlexW4298002814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.