Evidence map›Paper›PMID 36196310›Full record

ArticleCureus2022

Surface-Guided Patient Setup Versus Traditional Tattoo Markers for Radiation Therapy: Is Tattoo-Less Setup Feasible for Thorax, Abdomen and Pelvis Treatment?

Hui Zhao, Adam Paxton, Vikren Sarkar, Ryan G Price, Jessica Huang, Fan-Chi Frances Su, Xing Li, Prema Rassiah, Martin Szegedi, Bill Salter

Open access · diamondAbstract read
In one paragraph

Article in Cureus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Understanding Patient Perspectives on Radiation Tattoos.Advances in radiation oncology · 2026
    Article
  2. Multiregional assessment of surface guidance for patient positioning in radiotherapy.Technical innovations & patient support in radiation oncology · 2026
    Article
  3. Article
  4. A novel SGRT system for real-time optical surface tracking or guidance.Journal of applied clinical medical physics · 2025
    Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Hui ZhaoRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Adam PaxtonRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Vikren SarkarRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Ryan G PriceRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Jessica HuangRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Fan-Chi Frances SuRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Xing LiRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Prema RassiahRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Martin SzegediRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Bill SalterRadiation Oncology, University of Utah - Huntsman Cancer Institute, Salt Lake City, USA.
Huntsman Cancer Institute · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn this study, patient setup accuracy was compared between surface guidance and tattoo markers for radiation therapy treatment sites of the thorax, abdomen and pelvis. METHODS AND MATERIALS: A total of 608 setups performed on 59 patients using both surface-guided and tattoo-based patient setups were analyzed. During treatment setup, patients were aligned to room lasers using their tattoos, and then the six-degree-of-freedom (6DOF) surface-guided offsets were calculated and recorded using AlignRT system. While the patient remained in the same post-tattoo setup position, target localization imaging (radiographic or ultrasound) was performed and these image-guided shifts were recorded. Finally, surface-guided vs tattoo-based offsets were compared to the final treatment position (based on radiographic or ultrasound imaging) to evaluate the accuracy of the two setup methods.

resultsThe overall average offsets of tattoo-based and surface-guidance-based patient setups were comparable within 3.2 mm in three principal directions, with offsets from tattoo-based setups being slightly less. The maximum offset for tattoo setups was 2.2 cm vs. 4.3 cm for surface-guidance setups. Larger offsets (ranging from 2.0 to 4.3 cm) were observed for surface-guided setups in 14/608 setups (2.3%). For these same cases, the maximum observed tattoo-based offset was 0.7 cm. Of the cases with larger surface-guided offsets, 13/14 were for abdominal/pelvic treatment sites. Additionally, larger rotations (>3°) were recorded in 18.6% of surface-guided setups. The majority of these larger rotations were observed for abdominal and pelvic sites (~84%).

conclusionsThe small average differences observed between tattoo-based and surface-guidance-based patient setups confirm the general equivalence of the two potential methods, and the feasibility of tattoo-less patient setup. However, a significant number of larger surface-guided offsets (translational and rotational) were observed, especially in the abdominal and pelvic regions. These cases should be anticipated and contingency setup methods planned for.

Indexed as

radiation therapyrotationsurface-guided patient setuptattoo-less setuptranslation

Identifiers

PMID36196310
PMCPMC9525098
OpenAlexW4293917519

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.