ReviewRegenerative biomaterials2022
Recent advances in biopolymer-based hemostatic materials.
Review in Regenerative biomaterials, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 71 citations in OpenAlex.
- Development of Dual-Cross-Linked AlgMA/HAMA Hybrid Hydrogels for Traumatic Wound Healing.ACS omega · 2026Article
- Polysaccharides and carbohydrate polymers: innovations from nature to industry.Journal of the science of food and agriculture · 2026Review
- Review of recent advances in chitosan- and hyaluronic-acid-based wound dressings: fabrication, application, and types.Frontiers in pharmacology · 2026Review
- Dual-mode rapid hemostatic materials composed of gelatin and carboxymethyl cellulose for non-compressible bleeding in spinal surgery.Regenerative biomaterials · 2026Article
- Local delivery of tranexamic acid for hemorrhage control in trauma: a narrative review.Frontiers in drug delivery · 2026Review
- Three-Dimensional Printing and Supercritical Technologies for the Fabrication of Intricately Structured Aerogels Derived from the Alginate-Chitosan Polyelectrolyte Complex.Gels (Basel, Switzerland) · 2025Article
- Toward Natural Wound Healing Therapy: Honey andPharmaceutics · 2025Article
- Evaluation of Chitosan-Based Axiostat as Hemostatic Dressing for Endovascular Procedures in Patients with Leriche Syndrome on Anticoagulant Therapy.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Optimization and Preparation of Polysaccharide-Protamine Microspheres with Enhanced Hemostatic and Antibacterial Properties for Wound Healing.Marine drugs · 2025Article
- Green biosynthetic silver nanoparticles fromMaterials today. Bio · 2025Article
- Emulsion-Based Encapsulation of Fibrinogen with Calcium Carbonate for Hemorrhage Control.Journal of functional biomaterials · 2025Article
- Smart design in biopolymer-based hemostatic sponges: From hemostasis to multiple functions.Bioactive materials · 2025Review
- Influence of Lavender Essential Oil on the Physical and Antibacterial Properties of Chitosan Sponge for Hemostatic Applications.International journal of molecular sciences · 2023Article
- Bacterial-Nanocellulose-Based Biointerfaces and Biomimetic Constructs for Blood-Contacting Medical Applications.ACS materials Au · 2023Review
- Polydopamine-Coated Polycaprolactone Electrospun Nanofiber Membrane Loaded with Thrombin for Wound Hemostasis.Polymers · 2023Article
- Chitosan-Based Biomaterials for Hemostatic Applications: A Review of Recent Advances.International journal of molecular sciences · 2023Review
- AntibacterialInternational journal of molecular sciences · 2023Article
- Review
- Recent advances in the medical applications of hemostatic materials.Theranostics · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 2 institutions in 4 countries.
Funding
Abstract
Hemorrhage is the leading cause of trauma-related deaths, in hospital and prehospital settings. Hemostasis is a complex mechanism that involves a cascade of clotting factors and proteins that result in the formation of a strong clot. In certain surgical and emergency situations, hemostatic agents are needed to achieve faster blood coagulation to prevent the patient from experiencing a severe hemorrhagic shock. Therefore, it is critical to consider appropriate materials and designs for hemostatic agents. Many materials have been fabricated as hemostatic agents, including synthetic and naturally derived polymers. Compared to synthetic polymers, natural polymers or biopolymers, which include polysaccharides and polypeptides, have greater biocompatibility, biodegradability and processibility. Thus, in this review, we focus on biopolymer-based hemostatic agents of different forms, such as powder, particles, sponges and hydrogels. Finally, we discuss biopolymer-based hemostatic materials currently in clinical trials and offer insight into next-generation hemostats for clinical translation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.