Evidence map›Paper›PMID 36196122›Full record

ReviewNational science review2022

Shedding light on neurons: optical approaches for neuromodulation.

Shan Jiang, Xiang Wu, Nicholas J Rommelfanger, Zihao Ou, Guosong Hong

Open access · goldAbstract readReview
In one paragraph

Review in National science review, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 69 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Temporally Coordinated Activity among Motor Cortex, Thalamus, and Thalamic Reticular Nucleus Neurons during Rat Forelimb Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  5. Article
  6. Smart Nanotechnologies for Multimodal Neuromodulation and Brain Interfacing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Color-neutral and reversible tissue transparency enables longitudinal deep-tissue imaging in live mice.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Shan JiangDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0002-1567-2745
Xiang WuDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.
Nicholas J RommelfangerWu Tsai Neurosciences Institute, Stanford University, Stanford, CA 94305, USA.
Zihao OuDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.ORCID https://orcid.org/0000-0003-2987-7423
Guosong HongDepartment of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.
Neurosciences Institute · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Today's optical neuromodulation techniques are rapidly evolving, benefiting from advances in photonics, genetics and materials science. In this review, we provide an up-to-date overview of the latest optical approaches for neuromodulation. We begin with the physical principles and constraints underlying the interaction between light and neural tissue. We then present advances in optical neurotechnologies in seven modules: conventional optical fibers, multifunctional fibers, optical waveguides, light-emitting diodes, upconversion nanoparticles, optical neuromodulation based on the secondary effects of light, and unconventional light sources facilitated by ultrasound and magnetic fields. We conclude our review with an outlook on new methods and mechanisms that afford optical neuromodulation with minimal invasiveness and footprint.

Indexed as

neural interfacesoptical neuromodulationoptogenetics

Identifiers

PMID36196122
PMCPMC9522429
OpenAlexW4205098684

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.