Evidence map›Paper›PMID 36195874›Full record

ReviewJournal of inflammation (London, England)2022

Deeper insight into the role of IL-17 in the relationship beween hypertension and intestinal physiology.

Ze-Jun Yang, Tian-Tian Wang, Bo-Ya Wang, Han Gao, Cheng-Wei He, Hong-Wei Shang, Xin Lu, Ying Wang, Jing-Dong Xu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of inflammation (London, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ze-Jun Yang *Clinical Medicine of "5+3"program, School of Basic Medical Science, Capital Medical University, Beijing, China.
Tian-Tian Wang *Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Bo-Ya Wang *Eight Program of Clinical Medicine, Peking University People's Hospital, Beijing, China.
Han GaoDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Cheng-Wei HeDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Hong-Wei ShangMorphological Experiment Center, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Xin LuMorphological Experiment Center, School of Basic Medical Sciences, Capital Medical University, Beijing, China.
Ying WangDepartment of Dermatology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Jing-Dong XuDepartment of Physiology and Pathophysiology, School of Basic Medical Sciences, Capital Medical University, Beijing, China. xujingdong@ccmu.edu.cn.
Capital Medical University · CNPeking University · CN

Funding

National Natural Science Foundation of China 821714056,81373671
6 · The paper itself

Abstract

With the incidence of hypertension increasing worldwide, more and more the mechanisms of hypertension from the perspective of immunity have found. Intestinal microbiota as well as its metabolites relationship with hypertension has attracted great attention from both clinicians and investigators. However, the associations of hypertension with lesions of a large number of immune factors including IL-17, MCP-1, IL-6, TGF-β, IL-10 and others have not been fully characterized. In this review, after introducing the immune factors as the most potent anti/pro-hypertension agents known, we provide detailed descriptions of the IL-17 involved in the pathology of hypertension, pointing out the underlying mechanisms and suggesting the clinical indications.

Indexed as

Gut microbiotaHypertensionIL-10IL-17IL-6Immune factorsMCP-1TGF-β

Identifiers

PMID36195874
PMCPMC9530412
OpenAlexW4301431678

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.