Evidence map›Paper›PMID 36195738›Full record

ArticleScientific reports2022

A comparison of the chest radiographic and computed tomographic features of subclinical pulmonary tuberculosis.

Angela Lau, Christopher Lin, James Barrie, Christopher Winter, Gavin Armstrong, Mary Lou Egedahl, Alexander Doroshenko, Courtney Heffernan, Leyla Asadi, Dina Fisher and 4 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Tuberculosis in Pregnancy: An Updated Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Limitations of Chest Radiography in Diagnosing Subclinical Pulmonary Tuberculosis in Canada.Mayo Clinic proceedings. Innovations, quality & outcomes · 2023
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Angela LauThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Christopher LinThe Department of Family Medicine, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
James BarrieThe Department of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Christopher WinterThe Department of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Gavin ArmstrongThe Department of Radiology and Diagnostic Imaging, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Mary Lou EgedahlThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Alexander DoroshenkoThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Courtney HeffernanThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Leyla AsadiThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Dina FisherCumming School of Medicine, University of Calgary, Calgary, AB, Canada.
Catherine PaulsenThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Jalal MooljiThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Yiming HuangThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada.
Richard LongThe Department of Medicine, Faculty of Medicine and Dentistry, University of Alberta, Room 8325, Aberhart Centre, 11402 University Avenue, Edmonton, AB, T6G 2J3, Canada. richard.long@ualberta.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Subclinical pulmonary tuberculosis (PTB) is a recently described intermediate state of great interest, but about which little is known. This study sought to describe and compare the frequency of key radiologic features of subclinical PTB on chest radiograph (CXR) versus computed tomographic scan (CT), and to interpret the clinical and public health relevance of the differences. Diagnostic CXRs and CT scans of the thorax and neck in a 16-year cohort of subclinical PTB patients in Canada were re-acquired and read by two independent readers and arbitrated by a third reader. Logistic regression models were fit to determine how likely CXR features can be detected by CT scan versus CXR after adjustment for age and sex. Among 296 subclinical patients, CXRs were available in 286 (96.6%) and CT scans in 94 (32.9%). CXR features in patients with and without CT scans were comparable. Lung cavitation was 4.77 times (95% CI 1.95-11.66), endobronchial spread 19.36 times (95% CI 8.05-46.52), and moderate/far-advanced parenchymal disease 3.23 times (95% CI 1.66-6.30), more common on CT scan than CXR. We conclude that the extent to which CXRs under-detect key radiologic features in subclinical PTB is substantial. This may have public health and treatment implications.

Indexed as

Tuberculosis, PulmonaryCohort StudiesHumansRadiographyRadiography, ThoracicThoraxTomography, X-Ray Computed

Identifiers

PMID36195738
PMCPMC9531232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.