Evidence map›Paper›PMID 36195501›Full record

ArticleSurgery2023

Black patients are more likely to undergo parathyroidectomy for secondary hyperparathyroidism.

N Rhea Udyavar, JiYoon Ahn, Philip Crepeau, Lilah F Morris-Wiseman, Valerie Thompson, Yusi Chen, Dorry L Segev, Mara McAdams-DeMarco, Aarti Mathur

Open access · greenAbstract read
In one paragraph

Article in Surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

N Rhea UdyavarDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address: nudyava1@jhmi.edu.
JiYoon AhnDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Philip CrepeauDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Lilah F Morris-WisemanDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Valerie ThompsonDepartment of Surgery, New York University, Grossman School of Medicine and Langone Health, New York, NY.
Yusi ChenDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Dorry L SegevDepartment of Surgery, New York University, Grossman School of Medicine and Langone Health, New York, NY.
Mara McAdams-DeMarcoDepartment of Surgery, New York University, Grossman School of Medicine and Langone Health, New York, NY.
Aarti MathurDepartment of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD.
Johns Hopkins University · USNew York University · US

Funding

Clinical and Laboratory Research Training for Surgical OncologistsT32CA126607 · NCI · JOHNS HOPKINS UNIVERSITY · PI CAMERON, ANDREW M. · 2008 to 2024
$6.0M
Kidney transplantation in older, frail and cognitively impaired adults with ESRD: Balancing utility vs. justiceR01AG055781 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2017 to 2021
$4.2M
Cognitive Decline and Incident Dementia in Older Patients with Secondary HyperparathyroidismR01AG076834 · NIA · JOHNS HOPKINS UNIVERSITY · PI Aarti Mathur · 2023 to 2026
$3.3M
Developing personalized immunosuppression for older kidney transplant recipientsR01DK120518 · NIDDK · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI MCADAMS DEMARCO, MARA A. · 2019 to 2022
$2.7M
Association of Fraility with Post thyroidectomy alterations in Voice, Swallowing, and Quality of LifeK23AG053429 · NIA · JOHNS HOPKINS UNIVERSITY · PI MATHUR, AARTI · 2017 to 2022
$1.0M
Patient Oriented Research in Solid Organ TransplantationK24AI144954 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI SEGEV, DORRY L. · 2020 to 2024
$956k
Patient Oriented Research in Kidney Disease and Transplant SurgeryK24DK101828 · NIDDK · JOHNS HOPKINS UNIVERSITY · PI SEGEV, DORRY L. · 2014 to 2018
$922k
NCI NIH HHS T32 CA126607NIAID NIH HHS K24 AI144954NIA NIH HHS K23 AG053429NIA NIH HHS R01 AG055781NIA NIH HHS R01 AG076834NIDDK NIH HHS K24 DK101828NIDDK NIH HHS R01 DK120518
6 · The paper itself

Abstract

backgroundPrior studies have demonstrated racial disparities in the severity of secondary hyperparathyroidism among dialysis patients. Our primary objective was to study the racial and socioeconomic differences in the timing and likelihood of parathyroidectomy in patients with secondary hyperparathyroidism.

methodsWe used the United States Renal Data System to identify 634,428 adult (age ≥18) patients who were on maintenance dialysis between 2006 and 2016 with Medicare as their primary payor. Adjusted multivariable Cox regression was performed to quantify the differences in parathyroidectomy by race.

resultsOf this cohort, 27.3% (173,267) were of Black race. Compared to 15.4% of White patients, 23.1% of Black patients lived in a neighborhood that was below a predefined poverty level (P < .001). The cumulative incidence of parathyroidectomy at 10 years after dialysis initiation was 8.8% among Black patients compared to 4.3% among White patients (P < .001). On univariable analysis, Black patients were more likely to undergo parathyroidectomy (adjusted hazard ratio = 1.83; 95% confidence interval, 1.74-1.93). This association persisted after adjusting for age, sex, cause of end-stage renal disease, body mass index, comorbidities, dialysis modality, and poverty level (adjusted hazard ratio = 1.35; 95% confidence interval, 1.27-1.43). Therefore, patient characteristics and socioeconomic status explained 26% of the association between race and likelihood of parathyroidectomy.

conclusionBlack patients with secondary hyperparathyroidism due to end-stage renal disease are more likely to undergo parathyroidectomy with shorter intervals between dialysis initiation and parathyroidectomy. This association is only partially explained by patient characteristics and socioeconomic factors.

Indexed as

Hyperparathyroidism, SecondaryKidney Failure, ChronicAdultAgedHumansMedicareParathyroidectomyRisk FactorsUnited States

Identifiers

PMID36195501
PMCPMC10443691
OpenAlexW4298325853

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.