Evidence map›Paper›PMID 36194610›Full record

Observational studyPloS one2022

Evaluation of right ventricular function during liver transplantation with transesophageal echocardiography.

Glauber Gouvêa, John Feiner, Sonali Joshi, Rodrigo Diaz, Jose Eduardo Ferreira Manso, Alexandra Rezende Assad, Ismar Lima Cavalcanti, Marcello Fonseca Salgado-Filho, Aline D'Avila Pereira, Nubia Verçosa

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Glauber GouvêaPostGraduate Program of Surgical Sciences, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0003-3473-7951
John FeinerDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, United States of America.ORCID 0000-0001-6161-1209
Sonali JoshiDepartment of Anesthesia and Perioperative Care, University of California San Francisco, San Francisco, California, United States of America.
Rodrigo DiazClementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Jose Eduardo Ferreira MansoDepartment of Surgery, PostGraduate Program of Surgical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-9694-7415
Alexandra Rezende AssadDepartment of General and Specialized Surgery/Anesthesiology, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0002-7462-6079
Ismar Lima CavalcantiDepartment of General and Specialized Surgery/Anesthesiology, Fluminense Federal University, Niterói, Rio de Janeiro, Brazil.ORCID 0000-0002-0412-2609
Marcello Fonseca Salgado-FilhoPostGraduate Program in Anesthesia for High Risk Procedures, Israelita Albert Einstein Hospital, São Paulo, São Paulo, Brazil.
Aline D'Avila PereiraDepartment of Nutrition, University of Vassouras, Vassouras, Rio de Janeiro, Brazil.
Nubia VerçosaDepartment of Surgery, PostGraduate Program of Surgical Sciences, Federal University of Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0002-0400-2869
Universidade Federal do Rio de Janeiro · BRUniversidade Federal Fluminense · BRUniversity of California, San Francisco · USHospital Israelita Albert Einstein · BRUniversity of Vassouras · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe pathophysiology of advanced liver cirrhosis may induce alterations in the circulatory system that may be challenging for the anesthesiologist to manage intraoperatively, and perioperative cardiovascular events are associated with worse outcomes in cirrhotic patients undergoing liver transplantation. It remains controversial whether right ventricular function is impaired during this procedure. Studies using transesophageal echocardiography for quantitative analysis of the right ventricle remain scarce in this setting, yielding conflicting results. The aim of this study was to perform a quantitative assessment of right ventricular function with two parameters derived from transesophageal echocardiography during liver transplantation.

methodsNineteen adult patients of both genders undergoing liver transplantation were evaluated in this observational study. The exclusion criteria were age under 18 or above 65 years old, fulminant hepatic failure, hepatopulmonary syndrome, portopulmonary hypertension, cardiopulmonary disease, and contraindications to the transesophageal echocardiogram. Right ventricular function was assessed at five stages during liver transplantation: baseline, hepatectomy, anhepatic, postreperfusion, and closure by measuring tricuspid annular plane systolic excursion and right ventricular fractional area change obtained with transesophageal echocardiography.

resultsRight ventricular function was found to be normal throughout the procedure. The tricuspid annular plane systolic excursion showed a trend toward a decrease in the anhepatic phase compared to baseline (2.0 ± 0.9 cm vs. 2.4 ± 0.7 cm; P = 0.24) but with full recovery after reperfusion. Right ventricular fractional area change remained nearly constant during all stages studied (minimum: 50% ± 10 at baseline and anhepatic phase; maximum: 56% ± 12 at postreperfusion; P = 0.24).

conclusionsRight ventricular function was preserved during liver transplantation at the time points evaluated by two quantitative parameters derived from transesophageal echocardiogram.

Indexed as

Liver TransplantationVentricular Dysfunction, RightAdultAgedEchocardiography, TransesophagealFemaleHeart VentriclesHumansMaleVentricular Function, Right

Identifiers

PMID36194610
PMCPMC9531831
OpenAlexW4301374073

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.