Evidence map›Paper›PMID 36194551›Full record

ArticleACS synthetic biology2022

Engineering Endosymbiotic Growth of

Christoph G Gäbelein, Michael A Reiter, Chantal Ernst, Gabriel H Giger, Julia A Vorholt

Open access · hybridAbstract read
In one paragraph

Article in ACS synthetic biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Engineering signalling pathways in mammalian cells.Nature biomedical engineering · 2024
    Review
  7. Article
  8. Article
  9. Article
  10. Evolution and synthetic biology.Current opinion in microbiology · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Christoph G GäbeleinInstitute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Michael A ReiterInstitute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Chantal ErnstInstitute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Gabriel H GigerInstitute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.
Julia A VorholtInstitute of Microbiology, ETH Zurich, 8093 Zurich, Switzerland.ORCID 0000-0002-6011-4910
ETH Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endosymbioses are cellular mergers in which one cell lives within another cell and have led to major evolutionary transitions, most prominently to eukaryogenesis. Generation of synthetic endosymbioses aims to provide a defined starting point for studying fundamental processes in emerging endosymbiotic systems and enable the engineering of cells with novel properties. Here, we tested the potential of different bacteria for artificial endosymbiosis in mammalian cells. To this end, we adopted the fluidic force microscopy technology to inject diverse bacteria directly into the cytosol of HeLa cells and examined the endosymbiont-host interactions by real-time fluorescence microscopy. Among them,

Indexed as

Escherichia coliSymbiosisAmino Acids, AromaticAnimalsBacteriaBiological EvolutionHeLa CellsHumansMammalsAmino Acids, Aromaticcytosolic bacteriaendosymbiosesfluidic force microscopymetabolic engineeringsynthetic endosymbiosis

Identifiers

PMID36194551
PMCPMC9594318
OpenAlexW4301181118

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.