Evidence map›Paper›PMID 36194355›Full record

ArticleAnnals of nuclear medicine2022

Clinical impact of amyloid PET using

Hiroshi Matsuda, Kyoji Okita, Yumiko Motoi, Toshiki Mizuno, Manabu Ikeda, Nobuo Sanjo, Koji Murakami, Taiki Kambe, Toshiki Takayama, Kei Yamada and 12 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Annals of nuclear medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Sequential scans ofJapanese journal of radiology · 2026
    Article
  3. Article
  4. Plasma p-tau217 predicts PET-based pathological staging for precision Alzheimer disease assessment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  5. Comparison of visual and analytic methods of Alzheimer's disease pathologic staging.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Observational
  11. Article
  12. Incremental value of amyloid PET in a tertiary memory clinic setting in China.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 6 institutions in 1 country.

Hiroshi MatsudaDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan. matsudah@ncnp.go.jp.ORCID http://orcid.org/0000-0002-6297-9897
Kyoji OkitaIntegrative Bain Imaging Center, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Yumiko MotoiDepartment of Diagnosis, Prevention, and Treatment of Dementia, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Toshiki MizunoDepartment of Neurology, Kyoto Prefectural University of Medicine, 465 Kajiicho, Kamigyo Ward, Kyoto, 602-8566, Japan.
Manabu IkedaDepartment of Psychiatry, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Nobuo SanjoDepartment of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Koji MurakamiDepartment of Radiology, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Taiki KambeDepartment of Neurology, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Toshiki TakayamaDepartment of Psychiatry, Juntendo University Graduate School of Medicine, 3-1-3 Hongo, Bunkyo-ku, Tokyo, 113-8431, Japan.
Kei YamadaDepartment of Radiology, Kyoto Prefectural University of Medicine, 465 Kajiicho, Kamigyo Ward, Kyoto, 602-8566, Japan.
Takashi SuehiroDepartment of Psychiatry, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Keiko MatsunagaDepartment of Molecular Imaging in Medicine, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Takanori YokotaDepartment of Neurology and Neurological Science, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8510, Japan.
Ukihide TateishiDepartment of Diagnostic Radiology, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan.
Yoko ShigemotoDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Yukio KimuraDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Emiko ChibaDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Takahiro KawashimaDepartment of Clinical Data Science, Clinical Research & Education Promotion Division, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Yui TomoDepartment of Clinical Data Science, Clinical Research & Education Promotion Division, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Hisateru TachimoriDepartment of Clinical Data Science, Clinical Research & Education Promotion Division, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
Yuichi KimuraFaculty of Informatics, Cyber Informatics Research Institute, Kindai University、3-4-1, Kowakae, Higashiosaka, Osaka, 577-8502, Japan.
Noriko SatoDepartment of Radiology, National Center of Neurology and Psychiatry, 4-1-1, Ogawa-higashi, Kodaira, Tokyo, 187-8551, Japan.
National Center of Neurology and Psychiatry · JPJuntendo University · JPThe University of Osaka · JPTokyo Medical and Dental University · JPKyoto Prefectural University of Medicine · JPFukushima Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAmyloid positron emission tomography (PET) can reliably detect senile plaques and fluorinated ligands are approved for clinical use. However, the clinical impact of amyloid PET imaging is still under investigation. The aim of this study was to evaluate the diagnostic impact and clinical utility in patient management of amyloid PET using

methodsNinety-nine patients suspected of having AD underwent

resultsVisual interpretation obtained 48 positive and 51 negative PET scans. The amyloid PET results changed the AD and non-AD diagnosis in 39 of 99 patients (39.3%). The change rates of 26 of the 54 patients (48.1%) with a pre-scan AD diagnosis were significantly higher than those of 13 of the 45 patients with a pre-scan non-AD diagnosis (χ

conclusionAmyloid PET using

Indexed as

Alzheimer DiseaseAmyloidosisCognitive DysfunctionAmyloidAmyloid beta-PeptidesAniline CompoundsBrainEthylene GlycolsHumansPositron-Emission TomographyAmyloidAmyloid beta-PeptidesAniline CompoundsEthylene Glycolsflorbetapir18F-florbetapirAlzheimer’s diseaseAmyloidPET

Identifiers

PMID36194355
PMCPMC9668773
OpenAlexW4301393330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.