ArticleRadiology2023
Multicenter Reproducibility of Liver Iron Quantification with 1.5-T and 3.0-T MRI.
Registry-linked trialOpen access · greenAbstract readMulticenter Study
In one paragraph
Article in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02025543 (Confounder-Corrected Quantitative Magnetic Resonance Imaging), which is not on this map. Cited by 29 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
6.3field-weighted citation impact, top 3% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Confounder-Corrected Quantitative Magnetic Resonance Imaging (MRI) Biomarker of Hepatic Iron Content
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 42 citations in OpenAlex.
- Best practices for pediatric liver MRI: guidelines from members of the Society for Pediatric Radiology Magnetic Resonance and Abdominal Imaging Committees.Pediatric radiology · 2025Guideline
- Reproducibility of liver iron concentration measured by R2* method based on 1.5-T MRI: a meta-analysis.European radiology · 2025Pooled it
- Magnetic resonance imaging R2* mapping for evaluating Ki-67 proliferation index and cytokeratin 19 expression in solitary iron-sparing hepatocellular carcinoma: a retrospective single-center study.Quantitative imaging in medicine and surgery · 2026Article
- Single-Breathhold 3D MR Elastography in the Liver, With Simultaneous R2* and PDFF Mapping.Magnetic resonance in medicine · 2026Article
- Comparison of hepatic iron quantification by MRI between 1.5 and 3 T, using different methods and conversion formulas.European radiology · 2026Article
- Multi-scanner repeatability and reproducibility of qRF-MRF breath-held and free-breathing with pilot tone in the abdomen.Magma (New York, N.Y.) · 2026Article
- Clinical assessment of hepatic steatosis and iron content using three-dimensional (3D) multi-echo chemical shift encoded magnetic resonance imaging (MRI): correlation with histopathology.Quantitative imaging in medicine and surgery · 2026Article
- Evaluation of 0.55T MRI for Simultaneous R2* and Fat Fraction Quantification in the Presence of Hepatic Iron Overload and Steatosis Using Simulations and Phantoms.Magnetic resonance in medicine · 2026Article
- Generalized U-Net for automatic liver segmentation and R2* estimation for assessment of iron overload using MRI.BMC medical imaging · 2026Article
- Motion-Insensitive Flip Angle Modulated Liver Proton Density Fat-Fraction and R2* Mapping During Free-Breathing MRI in a Clinical Setting.Journal of magnetic resonance imaging : JMRI · 2025Observational
- Multi-Center, Multi-Vendor Validation of Simultaneous MRI-Based Proton Density Fat Fraction and R2* Mapping Using a Combined Proton Density Fat Fraction-R2* Phantom.Journal of magnetic resonance imaging : JMRI · 2025Article
- Whole liver phase-based R2 mapping in liver iron overload within a breath-hold.Magnetic resonance in medicine · 2025Article
- Impact of particle size onMagnetic resonance in medicine · 2025Article
- Quantification of Cardiac Iron Overload at 3 T MRI in a Rabbit Model Utilizing ME-GRE T2* Sequence.Journal of magnetic resonance imaging : JMRI · 2025Article
- State-of-the-Art Quantification of Liver Iron With MRI-Vendor Implementation and Available Tools.Journal of magnetic resonance imaging : JMRI · 2025Review
- Free-breathing qRF-MRF with pilot tone respiratory motion navigator for TMagma (New York, N.Y.) · 2025Article
- Multicenter, multivendor validation of liver quantitative susceptibility mapping in patients with iron overload at 1.5 T and 3 T.Magnetic resonance in medicine · 2025Observational
- Evaluating the efficacy of probiotics in treating Parkinson's disease model rats using magnetic resonance enhanced gradient echo T2-weighted angiography sequence.Frontiers in neuroscience · 2025Article
- Computed Tomography and Magnetic Resonance Imaging in Liver Iron Overload: From Precise Quantification to Prognosis Assessment.Biomedicines · 2024Review
- Diagnostic accuracy of an uncorrected native T1 mapping sequence for liver fibrosis and inflammation in autoimmune hepatitis: a prospective study using histopathology as reference standard.La Radiologia medica · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 1 institution in 2 countries.
Diego HernandoFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-0016-0317
Ruiyang ZhaoFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-2386-9767
Qing YuanFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0001-9851-0284
Mounes Aliyari GhasabehFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0001-7253-9310
Stefan RuschkeFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0001-9658-6541
Xinran MiaoFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0003-2042-3636
Dimitrios C KarampinosFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0003-4922-3662
Lu MaoFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-8626-9822
David T HarrisFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-1150-8702
Ryan J MattisonFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0001-8574-8365
Michael R JengFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0001-8200-8484
Ivan PedrosaFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-0371-8689
Ihab R KamelFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0003-0511-7796
Shreyas VasanawalaFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-1999-6595
Takeshi YokooFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0002-5092-6931
Scott B ReederFrom the Departments of Radiology (D.H., R.Z., D.T.H., S.B.R.), Medical Physics (D.H., R.Z., S.B.R.), Statistics (X.M.), Biostatistics and Medical Informatics (L.M.), Medicine (R.J.M.), Biomedical Engineering (S.B.R.), Medicine (S.B.R.), and Emergency Medicine, University of Wisconsin-Madison, 1111 Highland Ave, WIMR2, Room 2472, Madison, WI 53705 (S.B.R.); Department of Radiology (Q.Y., I.P., T.Y.) and Advanced Imaging Research Center (I.P., T.Y.), University of Texas Southwestern Medical Center, Dallas, Tex; Department of Radiology, The Johns Hopkins University, Baltimore, Md (M.A.G., I.R.K.); Department of Diagnostic and Interventional Radiology, School of Medicine, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany (S.R., D.C.K.); and Departments of Pediatrics (M.R.J.) and Radiology (S.V.), Stanford University, Palo Alto, Calif.ORCID 0000-0003-4728-8171
University of Wisconsin–Madison · US
Funding
Confounder-Corrected Quantitative MRI Biomarkers of HepaticR01DK100651 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2017
$2.7MMRI-based Quantitative Susceptibility Mapping of Hepatic Iron OverloadR01DK117354 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI HERNANDO, DIEGO · 2018 to 2021
$2.3MTechnical Development of Quantitative Biomarkers of Fatty Liver Disease with MRIR01DK083380 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2010 to 2013
$1.2MEvolution of Quantitative MRI Biomarkers of Metabolic Syndrome During PubertyK24DK102595 · NIDDK · UNIVERSITY OF WISCONSIN-MADISON · PI REEDER, SCOTT B. · 2014 to 2018
$927kNIDDK NIH HHS K24 DK102595NIDDK NIH HHS R01 DK083380NIDDK NIH HHS R01 DK100651NIDDK NIH HHS R01 DK117354
Abstract
Background MRI is a standard of care tool to measure liver iron concentration (LIC). Compared with regulatory-approved R2 MRI, R2* MRI has superior speed and is available in most MRI scanners; however, the cross-vendor reproducibility of R2*-based LIC estimation remains unknown. Purpose To evaluate the reproducibility of LIC via single-breath-hold R2* MRI at both 1.5 T and 3.0 T with use of a multicenter, multivendor study. Materials and Methods Four academic medical centers using MRI scanners from three different vendors (three 1.5-T scanners, one 2.89-T scanner, and two 3.0-T scanners) participated in this prospective cross-sectional study. Participants with known or suspected liver iron overload were recruited to undergo multiecho gradient-echo MRI for R2* mapping at 1.5 T and 3.0 T (2.89 T or 3.0 T) on the same day. R2* maps were reconstructed from the multiecho images and analyzed at a single center. Reference LIC measurements were obtained with a commercial R2 MRI method performed using standardized 1.5-T spin-echo imaging. R2*-versus-LIC calibrations were generated across centers and field strengths using linear regression and compared using
Indexed as
IronIron OverloadAdultCross-Sectional StudiesHumansLiverMagnetic Resonance ImagingMaleProspective StudiesReproducibility of ResultsIron
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Registered trials
NCT02025543ClinicalTrials.gov
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.