Observational studyRadiology2023
Understanding Reader Variability: A 25-Radiologist Study on Liver Metastasis Detection at CT.
Open access · greenAbstract readObservational Study
In one paragraph
Observational study in Radiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 13 citations in OpenAlex.
- Systematic review and meta-analysis of AI in lung cancer metastasis imaging for diagnosis and prognosis.NPJ digital medicine · 2026Article
- Reading, Fast and Slow: Characterizing Radiologists' Visual Search Through Abdominal CT for Detecting Hepatic Metastases.Academic radiology · 2026Article
- Anatomically constrained liver CT anomaly detection using healthy priors with diffusion-based inpainting.Research square · 2026Article
- Diagnostic Performance of a Next-Generation Virtual/Augmented Reality Headset: A Pilot Study of Diverticulitis on CT.Journal of imaging informatics in medicine · 2025Article
- Predictive and therapeutic value of the ferroptosis gene CISD1 in non?small cell lung cancer.Oncology letters · 2025Article
- Commentary on "Peripheral liver metastases are more frequently missed than central metastases in contrast enhanced CT: insights from a 25-reader performance study".Abdominal radiology (New York) · 2025Article
- Peripheral liver metastases are more frequently missed than central metastases in contrast-enhanced CT: insights from a 25-reader performance study.Abdominal radiology (New York) · 2025Article
- Distinct CT imaging features of new liver metastases from primary genitourinary cancers.Abdominal radiology (New York) · 2024Article
- 3D printed phantom with 12 000 submillimeter lesions to improve efficiency in CT detectability assessment.Medical physics · 2024Article
- Interpretation of Complete Tumor Response on MRI Following Chemoradiotherapy of Rectal Cancer: Inter-Reader Agreement and Associated Factors in Multi-Center Clinical Practice.Korean journal of radiology · 2024Article
- Targeted Training Reduces Search Errors but Not Classification Errors for Hepatic Metastasis Detection at Contrast-Enhanced CT.Academic radiology · 2024Article
- Diagnostic performance of computed tomography features in detecting oropharyngeal squamous cell carcinoma extranodal extension.European radiology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 1 country.
Scott S HsiehFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0001-5260-9211
David A CookFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0003-2383-4633
Akitoshi InoueFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).
Hao GongFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-1123-7172
Parvathy Sudhir PillaiFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0001-5160-1621
Matthew P JohnsonFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-6341-7220
Shuai LengFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-6453-9481
Lifeng YuFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-4267-1326
Jeff L FidlerFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0001-8275-126X
David R HolmesFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).
Rickey E CarterFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-0818-273X
Cynthia H McColloughFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-5346-332X
Joel G FletcherFrom the Departments of Radiology (S.S.H., A.I., H.G., P.S.P., S.L., L.Y., J.L.F., C.H.M., J.G.F.), General Internal Medicine (D.A.C.), Quantitative Health Services-Clinical Trials and Biostatistics (M.P.J.), and Physiology and Biomedical Engineering (D.R.H.), Mayo Clinic Rochester, 200 First St SW, Rochester, MN 55905; and Department of Quantitative Health Services-Clinical Trials and Biostatistics, Mayo Clinic, Jacksonville, Fla (R.E.C.).ORCID 0000-0002-8941-5434
Mayo Clinic · USMayo Clinic in Florida · US
Funding
Trade-offs in human observer performance, image quality metrics, and patient doseR01EB017095 · NIBIB · MAYO CLINIC ROCHESTER · PI Hao Gong, Cynthia H McCollough · 2012 to 2026
$7.0MNIBIB NIH HHS R01 EB017095
Abstract
Background Substantial interreader variability exists for common tasks in CT imaging, such as detection of hepatic metastases. This variability can undermine patient care by leading to misdiagnosis. Purpose To determine the impact of interreader variability associated with
Indexed as
Liver NeoplasmsAdultDiagnostic ErrorsHumansMaleRetrospective StudiesTomography, X-Ray Computed
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.