Evidence map›Paper›PMID 36194009›Full record

ArticleJournal of bacteriology2022

The DdrR Coregulator of the Acinetobacter baumannii Mutagenic DNA Damage Response Potentiates UmuDAb Repression of Error-Prone Polymerases.

Deborah Cook, Mollee D Flannigan, Belinda V Candra, Kaylee D Compton, Janelle M Hare

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.7field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Exploring the Multifaceted GenusJournal of microbiology and biotechnology · 2025
    Review
  7. Repression ofJournal of bacteriology · 2024
    Article
  8. DNA damage response coregulatorFrontiers in cellular and infection microbiology · 2023
    Article
  9. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Deborah CookDepartment of Biology and Chemistry, Morehead State Universitygrid.260234.1, Morehead, Kentucky, USA.
Mollee D FlanniganDepartment of Biology and Chemistry, Morehead State Universitygrid.260234.1, Morehead, Kentucky, USA.
Belinda V CandraDepartment of Biology and Chemistry, Morehead State Universitygrid.260234.1, Morehead, Kentucky, USA.
Kaylee D ComptonDepartment of Biology and Chemistry, Morehead State Universitygrid.260234.1, Morehead, Kentucky, USA.
Janelle M HareDepartment of Biology and Chemistry, Morehead State Universitygrid.260234.1, Morehead, Kentucky, USA.ORCID 0000-0001-5482-8143
Morehead State University · US

Funding

WKU Lead Faculty AwardP20GM103436 · NIGMS · UNIVERSITY OF LOUISVILLE · PI ERIC C ROUCHKA · 2012 to 2026
$60.1M
ZEBRAFISH VISUAL FUNCTION RECOVERY FOLLOWING OPTIC NERVE DAMAGEP20RR016481 · NCRR · UNIVERSITY OF LOUISVILLE · PI COOPER, NIGEL G.F. · 2001 to 2011
$34.8M
Mechanisms of Action of UmuD in Regulating DNA Damage-Induced Genes in a umuC- Deficient mutantR15GM085722 · NIGMS · MOREHEAD STATE UNIVERSITY · PI Janelle M Hare · 2009 to 2026
$1.8M
NCRR NIH HHS P20 RR016481NIGMS NIH HHS P20 GM103436NIGMS NIH HHS R15 GM085722
6 · The paper itself

Abstract

Acinetobacter baumannii strain 17978 is an opportunistic pathogen with a unique DNA damage repair response that lacks the LexA repressor but induces ~150 genes after DNA damage. It uses the UmuD homolog UmuDAb and the small protein DdrR, unique to Acinetobacter, to repress multiple horizontally acquired

Indexed as

Acinetobacter baumanniiAnti-Bacterial AgentsBacterial ProteinsDNA DamageDNA-Directed DNA PolymeraseMutagenesisMutagensAnti-Bacterial AgentsBacterial ProteinsDNA-Directed DNA PolymeraseMutagensAcinetobacter baumanniicorepressorsDdrRDNA damagehorizontal gene transferSOS mutagenesisUmuDAb

Identifiers

PMID36194009
PMCPMC9664961
OpenAlexW4301392541

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.