Article in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 46% of its field
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literature
Who cites it
1 citing paper in PubMed, 4 citations in OpenAlex.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
19 authors at 7 institutions in 2 countries.
Mengyao ShiDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0002-5883-0416
Tanika N KellyDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0002-7348-4451
Zhengbao ZhuDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.ORCID 0000-0001-5500-0014
Changwei LiDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0002-9203-304X
Chong ShenDepartment of Epidemiology, School of Public Health Nanjing Medical University Nanjing China.ORCID 0000-0001-6447-6591
Yingxian SunDepartment of Cardiology the First Affiliated Hospital of China Medical University Shenyang China.
Aili WangDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.
Guangliang ShanDepartment of Epidemiology, School of Basic Medicine Peking Union Medical College Beijing China.
Xiaoqing BuDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.
Daoxia GuoDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.
Jingbo ZhaoDepartment of Epidemiology, School of Public Health Harbin Medical University Harbin China.
Tan XuDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.
Hao PengDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.ORCID 0000-0001-6277-662X
Tian XuDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.ORCID 0000-0001-9278-1622
Chongke ZhongDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.ORCID 0000-0003-2314-6814
Xiao SunDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0001-8802-2957
Jing ChenDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0002-9035-9126
Yonghong ZhangDepartment of Epidemiology School of Public Health, and Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases Medical College of Soochow University Suzhou China.ORCID 0000-0001-6188-3490
Jiang HeDepartment of Epidemiology Tulane University School of Public Health and Tropical Medicine New Orleans LA.ORCID 0000-0002-8286-9652
Soochow University · CNTulane University · USNantong University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNFirst Hospital of China Medical University · CNHarbin Medical University · CNNanjing Medical University · CN
Funding
No grant is acknowledged in the PubMed record.
6 · The paper itself
Abstract
Background Ischemic stroke is likely caused by interactions of multiple genes and environmental determinants. However, large-scale sequencing studies to discern functional genetic variants and their interactions with clinical and lifestyle risk factors on ischemic stroke are limited. Methods and Results We sequenced functional regions of 740 previously identified genes associated with atherosclerotic disease among 999 ischemic stroke cases and 1001 controls of Chinese ancestry. Multiple logistic regression models were used to examine the associations between variants and ischemic stroke and test interactions between variants and clinical and lifestyle risk factors. Functional variants achieving suggestive significance were replicated in an independent sample of 4724 ischemic stroke cases and 5029 controls. Driven by variant main effects, each minor allele of the correlated rs174535, rs174545, and rs3834458 variants at
Indexed as
Ischemic StrokeStrokeAldehyde Dehydrogenase, MitochondrialAsian PeopleCase-Control StudiesChinaGenetic Predisposition to DiseaseHomocysteineHumansPolymorphism, Single NucleotideRisk FactorsTranscription FactorsAldehyde Dehydrogenase, MitochondrialALDH2 protein, humanHomocysteineTranscription Factorsgene–environment interactiongenetic analysisischemic stroketargeted sequencing study
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Large-Scale Targeted Sequencing Study of Ischemic Stroke in the Han Chinese Population. · full record | OpenQuestion