Evidence map›Paper›PMID 36193755›Full record

Trial reportThe British journal of radiology2022

Artificial intelligence-based model for COVID-19 prognosis incorporating chest radiographs and clinical data; a retrospective model development and validation study.

Shannon L Walston, Toshimasa Matsumoto, Yukio Miki, Daiju Ueda

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in The British journal of radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shannon L WalstonDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka City University, 1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Toshimasa MatsumotoDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University,1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Yukio MikiDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University,1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.
Daiju UedaDepartment of Diagnostic and Interventional Radiology, Graduate School of Medicine, Osaka Metropolitan University,1-4-3 Asahi-machi, Abeno-ku, Osaka, Japan.ORCID 0000-0002-3878-3616

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of this study was to develop an artificial intelligence-based model to prognosticate COVID-19 patients at admission by combining clinical data and chest radiographs.

methodsThis retrospective study used the Stony Brook University COVID-19 dataset of 1384 inpatients. After exclusions, 1356 patients were randomly divided into training (1083) and test datasets (273). We implemented three artificial intelligence models, which classified mortality, ICU admission, or ventilation risk. Each model had three submodels with different inputs: clinical data, chest radiographs, and both. We showed the importance of the variables using SHapley Additive exPlanations (SHAP) values.

resultsThe mortality prediction model was best overall with area under the curve, sensitivity, specificity, and accuracy of 0.79 (0.72-0.86), 0.74 (0.68-0.79), 0.77 (0.61-0.88), and 0.74 (0.69-0.79) for the clinical data-based model; 0.77 (0.69-0.85), 0.67 (0.61-0.73), 0.81 (0.67-0.92), 0.70 (0.64-0.75) for the image-based model, and 0.86 (0.81-0.91), 0.76 (0.70-0.81), 0.77 (0.61-0.88), 0.76 (0.70-0.81) for the mixed model. The mixed model had the best performance (

conclusionsThese results suggest that prognosis models become more accurate if AI-derived chest radiograph features and clinical data are used together. ADVANCES IN KNOWLEDGE: This AI model evaluates chest radiographs together with clinical data in order to classify patients as having high or low mortality risk. This work shows that chest radiographs taken at admission have significant COVID-19 prognostic information compared to clinical data other than age and sex.

Indexed as

COVID-19Artificial IntelligenceHumansPrognosisRadiographyRetrospective Studies

Identifiers

PMID36193755
PMCPMC9733620

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.