Evidence map›Paper›PMID 36193535›Full record

ArticleHeliyon2022

Wheat germ oil vitamin E cytoprotective effect and its nutrigenomics signature in human hepatocyte lipotoxicity.

Desirée Bartolini, Rita Marinelli, Anna Maria Stabile, Tiziana Frammartino, Angela Guerrini, Stefano Garetto, Jacopo Lucci, Anna Migni, Linda Zatini, Giada Marcantonini and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Role of oxidative stress in male infertility.Reproduction & fertility · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Desirée BartoliniDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
Rita MarinelliDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
Anna Maria StabileDepartment of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy.
Tiziana FrammartinoNatural Bio-Medicine SpA, Loc. Aboca 20, 52037 Sansepolcro, AR, Italy.
Angela GuerriniNatural Bio-Medicine SpA, Loc. Aboca 20, 52037 Sansepolcro, AR, Italy.
Stefano GarettoNatural Bio-Medicine SpA, Loc. Aboca 20, 52037 Sansepolcro, AR, Italy.
Jacopo LucciNatural Bio-Medicine SpA, Loc. Aboca 20, 52037 Sansepolcro, AR, Italy.
Anna MigniDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
Linda ZatiniDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
Giada MarcantoniniDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
Mario RendeDepartment of Medicine and Surgery, Section of Human, Clinical and Forensic Anatomy, University of Perugia, Perugia, Italy.
Francesco GalliDepartment of Pharmaceutical Sciences, Lipidomics and Micronutrient Vitamins Lab. and Human Anatomy Lab., University of Perugia, 06126 Perugia, Italy.
University of Perugia · ITAboca (Italy) · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wheat germ oil (WGO) is rich in α-tocopherol (vitamin E, VE), a vitamin that has long been suggested to exert hepatoprotective effects. In this study, this function of WGO-VE and its transcriptomics fingerprint were investigated in comparison with RRR-α-tocopherol and

Indexed as

Alpha-tocopherolHuman hepatocytesLipotoxicityLiverNAFLDNASHNutrigenomicsPrecision nutritionReactive oxygen speciesTranscriptomicsVitamin EWheat germ oil

Identifiers

PMID36193535
PMCPMC9525900
OpenAlexW4296890744

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.