Evidence map›Paper›PMID 36193422›Full record

ArticlePeerJ2022

Ac2-26 attenuates hepatic ischemia-reperfusion injury in mice

Wanzhen Li, Hongxin Jiang, Chen Bai, Shuna Yu, Yitong Pan, Chenchen Wang, Huiting Li, Ming Li, Yaxin Sheng, Fangfang Chu and 4 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PeerJ, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. International journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Wanzhen Li *Department of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Hongxin Jiang *Morphology Lab, Weifang Medical University, Weifang, Shandong, China.
Chen BaiDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Shuna YuDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Yitong PanDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Chenchen WangDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Huiting LiDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Ming LiDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Yaxin ShengDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Fangfang ChuDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Jie WangDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Yuting ChenDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Jianguo LiDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Jiying JiangDepartment of Anatomy, Weifang Medical University, Weifang, Shandong, China.
Weifang Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatic ischemia-reperfusion injury (HIRI) is one of the major sources of mortality and morbidity associated with hepatic surgery. Ac2-26, a short peptide of Annexin A1 protein, has been proved to have a protective effect against IRI. However, whether it exerts a protective effect on HIRI has not been reported. The HIRI mice model and the oxidative damage model of H

Indexed as

Hydrogen PeroxideReperfusion InjuryAnimalsAnnexin A2Interleukin-22LiverMicePeptide FragmentsRatsRats, Sprague-DawleyReceptors, InterleukinSignal TransductionAnnexin A2Hydrogen PeroxideInterleukin-22interleukin-22 receptorPeptide FragmentsReceptors, InterleukinAc2-26ApoptosisHepatic ischemia-reperfusion injuryInflammatoryOxidative stress injury

Identifiers

PMID36193422
PMCPMC9526407
OpenAlexW4297545618

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.