Evidence map›Paper›PMID 36193310›Full record

ArticleBioMed research international2022

Seroprevalence of Anti-tTg-IgA among Symptomized Celiac Disease Patients and Their Correlation with Rotavirus Infection.

Asma Sadiq, Jadoon Khan, Irfan Ullah, Nosheen Basharat, Sajid Ali, Ahmad Ud Din, Ijaz Ali, Arshad Farid, Muddaser Shah, Mohamed M Abdel-Daim and 2 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 2 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Viruses and celiac disease: what do we know ?Clinical and experimental medicine · 2023
    Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 5 countries.

Asma SadiqDepartment of Microbiology, University of Jhang, Jhang, Pakistan.ORCID https://orcid.org/0000-0002-1962-6447
Jadoon KhanDepartment of Microbiology, Quaid-i-Azam University, Islamabad, Pakistan.ORCID https://orcid.org/0000-0002-7302-6987
Irfan UllahDepartment of Life Sciences, School of Science, University of Management and Technology (UMT), Lahore, Pakistan.
Nosheen BasharatMolecular Virology Laboratory, Department of Biosciences, COMSATS University, Islamabad, Pakistan.
Sajid AliInstitute of Biotechnology and Microbiology, Bacha Khan University, Charsadda, Pakistan.
Ahmad Ud DinInstitutes for Systems Genetics, West-China Hospital, Sichuan University, China.ORCID https://orcid.org/0000-0001-9879-2023
Ijaz AliMolecular Virology Laboratory, Department of Biosciences, COMSATS University, Islamabad, Pakistan.
Arshad FaridGomal Center of Biochemistry and Biotechnology, Gomal University, D.I. Khan 29059, Pakistan.
Muddaser ShahDepartment of Botany, Abdul Wali Khan University Mardan, Mardan 23200, Pakistan.
Mohamed M Abdel-DaimDepartment of Pharmaceutical Sciences, Pharmacy Program, Batterjee Medical College, P.O. Box 6231, Jeddah 21442, Saudi Arabia.ORCID https://orcid.org/0000-0002-4341-2713
Ghadeer M AlbadraniDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID https://orcid.org/0000-0001-5657-4650
Imtiaz Ali KhanCOMSATS University, Islamabad, Abbottabad Campus, Abbottabad, KP, Pakistan.
COMSATS University Islamabad · PKAbdul Wali Khan University Mardan · PKBacha Khan University · PKGomal University · PKPrincess Nourah bint Abdulrahman University · SAQuaid-i-Azam University · PKSichuan University · CNSuez Canal University · EGUniversity of Management and Technology · PK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) is a chronic inflammatory disorder in the intestinal tract as a response to the use of gluten in genetically predisposed individuals. It is a worldwide problem, with a high prevalence rate in North America. This is a descriptive cross-sectional study involving 1090 samples collected from different hospitals of Rawalpindi and Islamabad, Pakistan, from January 2019 to December 2019. In this study, 1090 blood samples screened for seroprevalence of anti-tTG antibodies in CD symptomatic patients via ELISA (enzyme-linked immunosorbent assay). 1090 fecal samples from the same CD patients were collected and tested for the presence of rotavirus (RV) via ELISA and RT-PCR. Of the 1090 patients tested for seroprevalence of anti-tTG antibodies, 112/1090 (10.3%) were found to be positive. Of the 112 anti-tTG-positive patients, 78/112 (70%) were positive for RV via ELISA and 74/112 (66.1%) were RV positive via RT-PCR. A statistically significant association was reported between rotavirus infection and celiac disease (

Indexed as

Celiac DiseaseRotavirus InfectionsAdolescentAutoantibodiesChildChild, PreschoolCross-Sectional StudiesEnzyme-Linked Immunosorbent AssayGlutensHumansImmunoglobulin ASeroepidemiologic StudiesTransglutaminasesAutoantibodiesGlutensImmunoglobulin ATransglutaminases

Identifiers

PMID36193310
PMCPMC9526599
OpenAlexW4296916593

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.