ArticleEuropean journal of plastic surgery2023
Bromelain-based enzymatic burn debridement: Spanish multidisciplinary consensus.
Article in European journal of plastic surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 17 citations in OpenAlex.
- Bromelain-based enzymatic burn debridement: A systematic review of clinical studies on patient safety, efficacy and long-term outcomes.International wound journal · 2023Pooled it
- Japanese Consensus Document on NexoBridEuropean burn journal · 2026Article
- Nexobrid Use in the Elderly.European burn journal · 2025Article
- An Analysis of Regional Blocks During Enzymatic Debridement of Burns.Journal of burn care & research : official publication of the American Burn Association · 2025Article
- Pain Management in Burned Patients Treated with Bromelain-Based Enzymatic Debridement.Journal of clinical medicine · 2025Article
- Bromelain in Burn Care: Advancements in Enzymatic Debridement and Patient Outcomes.European burn journal · 2024Review
- CONSENSUS ON THE APPLICATION AND CARE OF BROMELAIN-BASED ENZYMATIC DEBRIDEMENT ON BURNS.Annals of burns and fire disasters · 2024Article
- Enzymatic Debridement (Nexobrid) on Burned Hands: Retrospective Review from a Burn Referral Center in Spain.Plastic and reconstructive surgery. Global open · 2024Article
- Enzymatic Debridement of Deep Thermal Burns in the Russian Federation: First Experience.Life (Basel, Switzerland) · 2023Article
- Progress in Pluronic F127 Derivatives for Application in Wound Healing and Repair.International journal of nanomedicine · 2023Review
- Burn Debridment - Approach and Review.Current health sciences journalReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors at 8 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Bromelain-based enzymatic debridement is gaining increased interest from burn specialists in the last few years. The objective of this manuscript is to update the previous, first Spanish consensus document from 2017 (Martínez-Méndez et al. 43:193-202, 2017), on the use of enzymatic debridement with NexoBrid Methods: A consensus guideline was established by following a modified Delphi methodology of a 38-topic survey in two rounds of participation. Items were grouped in six domains: general indication, indication in critical patients, pain management, conditions for NexoBrid Results: In the first round, experts established consensus (strongly agree or agree) on 13 of the 38 statements. After the second round, a consensus was reached on 24 of the 25 remaining statements (97.2%). Conclusions: The present updated consensus document provides recommendations on the use of bromelain-based enzymatic debridement NexoBrid Level of evidence Not ratable:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.