Evidence map›Paper›PMID 36193235›Full record

ArticleResuscitation plus2022

Suction cup on a piston-based chest compression device improves coronary perfusion pressure and cerebral oxygenation during experimental cardiopulmonary resuscitation.

Johan Mälberg, David Smekal, Silvia Marchesi, Miklós Lipcsey, Sten Rubertsson

Abstract read
In one paragraph

Article in Resuscitation plus, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Johan MälbergEmergency Medical Service (EMS), Uppsala University Hospital, Sjukhusvägen, 75185 Uppsala, Sweden.
David SmekalEmergency Medical Service (EMS), Uppsala University Hospital, Sjukhusvägen, 75185 Uppsala, Sweden.
Silvia MarchesiJolife/Stryker AB, Scheelevägen 23633, Lund, Sweden.
Miklós LipcseyAnesthesia and Intensive Care Service, Surgical Science Department Sjukhusvägen, 75185, Uppsala University, Uppsala, Sweden.
Sten RubertssonAnesthesia and Intensive Care Service, Surgical Science Department Sjukhusvägen, 75185, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The presented study aimed to investigate whether a mechanical chest compression piston device with a suction cup assisting chest recoil could impact the hemodynamic status when compared to a bare piston during cardiopulmonary resuscitation. Methods: 16 piglets were anesthetized and randomized into 2 groups. After 3 minutes of induced ventricular fibrillation, a LUCAS 3 device was used to perform chest compressions, in one group a suction cup was mounted on the device's piston, while in the other group, compressions were performed by the bare piston. The device was used in 30:2 mode and the animals were manually ventilated. Endpoints of the study were: end tidal carbon dioxide, coronary and cerebral perfusion pressures, and brain oxygenation (measured using near infrared spectroscopy). At the end of the protocol, the animals that got a return to spontaneous circulation were observed for 60 minutes, then euthanized. Results: No difference was found in end tidal carbon dioxide or tidal volumes. Coronary perfusion pressure and cerebral oxygenation were higher in the Suction cup group over the entire experiment time, while cerebral perfusion pressure was higher only in the last 5 minutes of CPR. A passive tidal volume (air going in and out the airways during compressions) was detected and found correlated to end tidal carbon dioxide. Conclusions: The use of a suction cup on a piston-based chest compression device did not increase end tidal carbon dioxide, but it was associated to a higher coronary perfusion pressure.

Indexed as

ANOVA, analysis of varianceCerebral oxygenation, suction cupCerPP, cerebral perfusion pressureCoronary perfusion pressureCPP, coronary perfusion pressureCPR, cardiopulmonary resuscitationCVP, central venous pressureEtCO2, end tidal carbon dioxideFiO2, inspirated fraction of oxygenICP, intracranial pressureMechanical chest compressionNIRS, near infrared spectroscopyPbtO2, partial pressure of tissue oxygenPEEP, positive end expiratory pressurePiston-based deviceROSC, return to spontaneous circulationSD, standard deviationSrO2, cerebral oxygen saturationtV, tidal volumeVF, ventricular fibrillation

Identifiers

PMID36193235
PMCPMC9525897

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.