Evidence map›Paper›PMID 36193087›Full record

ArticleOxidative medicine and cellular longevity2022

Synthesis and Characterization of a Novel Dual-Responsive Nanogel for Anticancer Drug Delivery.

Darya Aminoleslami, Sahar Porrang, Parviz Vahedi, Soodabeh Davaran

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 1 country.

Darya AminoleslamiResearch Centre for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.
Sahar PorrangChemical Engineering Faculty, Sahand University of Technology, Sahand New Town, Tabriz, Iran.
Parviz VahediDepartment of Anatomical Sciences, Maragheh University of Medical Sciences, Maragheh, Iran.ORCID https://orcid.org/0000-0001-6662-6768
Soodabeh DavaranResearch Centre for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, Tabriz, Iran.ORCID https://orcid.org/0000-0002-7072-2362
Tabriz University of Medical Sciences · IRSahand University of Technology · IRUniversity of Maragheh · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, to reduce the side effects of anticancer drugs and also to increase the efficiency of current drug delivery systems, a pH and temperature-responsive polymeric nanogel was synthesized by copolymerization of N-vinylcaprolactam (VCL) and acrylic acid (AA) monomers (P(VCL-co-AA)) with a novel cross-linker, triethylene glycol dimethacrylate (TEGDMA), as a biocompatible and nontoxic component. The structural and physicochemical features of the P(VCL-co-AA) nanogel were characterized by FT-IR, DLS/Zeta potential, FE-SEM, and

Indexed as

Antineoplastic AgentsDrug CarriersCarbonDoxorubicinDrug Delivery SystemsDrug LiberationHumansHydrogen-Ion ConcentrationNanogelsPolyethylene GlycolsPolyethyleneimineSpectroscopy, Fourier Transform InfraredAntineoplastic AgentsCarbonDoxorubicinDrug CarriersNanogelspolyethylene glycol polyethyleneimine nanogelPolyethylene GlycolsPolyethyleneimine

Identifiers

PMID36193087
PMCPMC9526620
OpenAlexW4296462569

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.