Evidence map›Paper›PMID 36193025›Full record

ArticleCancer reports (Hoboken, N.J.)2022

A case report on non-metastatic Ewing sarcoma of the lumbar spine in a young patient.

Shobha Mandal, Srijana Baniya, Dipesh Kumar Rohita, Gopal Kumar Yadav, Philip Lowry

Open access · goldAbstract readCase Reports
In one paragraph

Article in Cancer reports (Hoboken, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Shobha MandalDepartment of Internal Medicine, Guthrie Robert Packer Hospital, Sayre, Pennsylvania, USA.
Srijana BaniyaDepartment of Internal Medicine, Penn State College of Medicine, Hershey, Pennsylvania, USA.
Dipesh Kumar RohitaDepartment of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal.ORCID 0000-0003-3045-1980
Gopal Kumar YadavDepartment of Internal Medicine, BP Koirala Institute of Health Sciences, Dharan, Nepal.ORCID 0000-0002-2195-9152
Philip LowryDepartment of Internal Medicine, Guthrie Robert Packer Hospital, Sayre, Pennsylvania, USA.
B.P. Koirala Institute of Health Sciences · NPSUNY Upstate Medical University · USPenn State Milton S. Hershey Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEwing sarcoma (ES), the second most common malignant bone tumor after osteosarcoma in the second decade, occurs in 0.9% of cases as the primary non-sacral form. CASE: A 20-years-old male presented with acute paraparesis of bilateral lower limb and numbness following initial back pain for the last 6 months. Magnetic resonance imaging (MRI) of the lumbar spine revealed a 4 cm enhancing soft tissue mass at the L4/L5 vertebra extending into the spinal canal with compression of the thecal sac. The computed tomography (CT) of the chest, abdomen, and pelvis revealed aggressive lytic lesions in the L4 spinous process with soft tissue extension into the spinal canal with no other site of distant metastasis. He was treated with IV steroids (Injection dexamethasone 10 mg IV followed by 4 mg tablet dexamethasone q6h; subsequently tapered off). A core needle biopsy showed a small, round blue cell neoplasm, (suggestive of a primitive neuroectodermal) stained positive for CD99 and vimentin stain. The diagnosis of ES lumbar spine was made which was treated with surgical resection with an appropriate margin measuring 8 × 4.5 × 2.5 cm with decompression and L4/5 laminectomies, which had a negative margin in the surgical pathology report. Concomitant local radiotherapy and chemotherapy [cycles of vincristine 2 mg/m

conclusionsThe presentation of lumbar ES can vary from local pain and swelling to acute paraparesis. Timely diagnosis and treatment with multimodal therapy, namely, steroids for acute spinal cord compression and surgery with chemoradiotherapy for ES can improve spinal biomechanics and oncological control.

Indexed as

Bone NeoplasmsNeoplasms, Second PrimarySarcoma, EwingAdultDexamethasoneHumansMaleParaparesisSpineYoung AdultDexamethasonecase reportEwing sarcomalaminectomylumbar spinespinal neoplasm

Identifiers

PMID36193025
PMCPMC9675370
OpenAlexW4300818896

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.