Evidence map›Paper›PMID 36192799›Full record

ArticleJournal of medical case reports2022

Aseptic meningitis in multisystem inflammatory syndrome in children associated with coronavirus disease 2019: a case report.

Alije Keka-Sylaj, Atifete Ramosaj, Arbana Baloku, Qëndresa Beqiraj, Petrit Gjaka

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of medical case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 2 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Alije Keka-SylajInstitute of Anatomy, Pediatric Clinic, Faculty of Medicine, University of Prishtina, Pristina, 10000, Kosovo. alije.keka@uni-pr.edu.
Atifete RamosajInstitute of Anatomy, Pediatric Clinic, Faculty of Medicine, University of Prishtina, Pristina, 10000, Kosovo.
Arbana BalokuPediatric Clinic, University Clinical Center of Kosovo, Pristina, 10000, Kosovo.
Qëndresa BeqirajPediatric Clinic, University Clinical Center of Kosovo, Pristina, 10000, Kosovo.
Petrit GjakaPediatric Clinic, University Clinical Center of Kosovo, Pristina, 10000, Kosovo.
University Clinical Center of Kosovo · XKUniversity of Prishtina · XK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs the coronavirus disease 2019 infections are still ongoing, there is an increasing number of case reports and case series with various manifestations of life-threatening multisystem inflammatory syndrome in children . Our case aims to remind all providers to scrutinize for clinical manifestations, including neurological symptoms, which may mimic aseptic meningitis. CASE PRESENTATION: A 5-year-old Albanian male child with obesity was admitted to the pediatric intensive care unit due to persistent fever, headache, vomiting, abdominal pain, mucocutaneous manifestations, and fatigue. Initial laboratory results revealed high level of inflammatory markers, including C-reactive protein of 156.8 mg/l, erythrocyte sedimentation rate of 100 mm/hour, procalcitonin of 13.84, leukocytosis with neutrophilia, and lymphopenia. Liver and renal functions, and capillary blood electrolytes (Na, K, Ca), were also altered. Cerebrospinal fluid was slightly turbid, with a white blood cell count of 128/mm

conclusionsApart from the most common presentation of multisystem organ dysfunction, neurological manifestations of multisystem inflammatory syndrome in children such as aseptic meningitis, may be present as an immune response post-viral to coronavirus disease 2019. Given the rapid deterioration of children with multisystem inflammatory syndrome, early treatment with immunoglobulins and corticosteroids should be considered.

Indexed as

Connective Tissue DiseasesCOVID-19Meningitis, AsepticChildChild, PreschoolC-Reactive ProteinHumansImmunoglobulins, IntravenousMaleMethylprednisoloneProcalcitoninSARS-CoV-2Systemic Inflammatory Response SyndromeC-Reactive ProteinImmunoglobulins, IntravenousMethylprednisoloneProcalcitoninAseptic meningitisChildrenCOVID 19MIS-C

Identifiers

PMID36192799
PMCPMC9529331
OpenAlexW4300716364

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.