ArticleBMC public health2022
Nutrition-related diseases and cardiovascular mortality in American society: national health and nutrition examination study, 1999-2006.
Article in BMC public health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Malnutrition-Sarcopenia Syndrome in older adults: Causes, consequences, and countermeasures.EXCLI journal · 2026Review
- Study on influencing factors of anxiety symptoms and its association with nutritional condition in elderly heart failure patients.Frontiers in nutrition · 2026Article
- Association between dietary quality index-international (DQI-I) and cardiovascular diseases: insights from RaNCD cohort study.BMC nutrition · 2025Article
- Association between skeletal muscle mass and the prognosis of patients undergoing percutaneous coronary intervention: a retrospective study.BMC cardiovascular disorders · 2025Article
- Nutrition and eating beliefs and behaviors among individuals with spinal cord injuries and disorders: Healthy or misconceived?Rehabilitation psychology · 2025Article
- Clinical Competency in Managing Malnutrition-Sarcopenia Syndrome Among Physical Therapists: A Cross-Sectional Survey.Nutrients · 2025Article
- Cardiovascular Risk Factors as Predictors of Nutritional Status in Older Mexican Adults.Nutrients · 2024Article
- Low lean mass with obesity in older adults with hypertension: prevalence and association with mortality rate.BMC geriatrics · 2023Article
- Nutrition knowledge, attitudes, and dietary practices among parents of children and adolescents in Weifang, China: A cross-sectional study.Preventive medicine reports · 2023Article
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8 authors.
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Abstract
backgroundDespite many significant advances in treatment and management, cardiovascular disease remains the main cause of the global disease burden. Nutrition-related disease is a modifiable cardiovascular risk factor. However, few studies have examined the relationship between nutrition-related diseases and cardiovascular mortality.
objectiveWe aimed to investigate the association of nutrition-related diseases with cardiovascular mortality based on a large nationally representative community population.
designWe analyzed data from the National Health and Nutrition Examination Survey (NHANES) 1999-2006 with mortality follow-up through December 31, 2015. Finally, 12,469 participants were analyzed. Each participant was assigned to one of four groups: normal nutrition without sarcopenia, sarcopenia with normal nutrition, malnutrition without sarcopenia, and malnutrition-sarcopenia syndrome. Survival curves and Cox regressions based on the NHANES recommended weights were used to assess the association between nutrition-related diseases and cardiovascular mortality.
resultsOf the 12,469 patients included in the study and divided into four groups, malnutrition-sarcopenia syndrome had the highest 5- and 10-year cardiovascular mortality rates. After adjustment for related factors, sarcopenia with normal nutrition (hazard ratio [HR]: 1.62, 95% confidence interval [CI]: 1.28-2.06; P < 0.001), malnutrition without sarcopenia (HR: 1.28, 95% CI:1.03-1.58; P = 0.024), and malnutrition-sarcopenia syndrome (HR: 2.66, 95% CI:1.89 - 3.74; P < 0.001) were significantly associated with increased risk of all-cause mortality. Malnutrition-sarcopenia syndrome remained associated with an increased risk of cardiovascular mortality (HR: 3.56, 95% CI: 1.17 - 10.84; P < 0.001).
conclusionsMalnutrition-sarcopenia syndrome was highly prevalent among community-dwelling adults in the United States and was a strong prognostic factor for cardiovascular mortality in the community setting. Randomized clinical trials are needed to demonstrate whether prevention or treatment of malnutrition-sarcopenia syndrome in community populations can reduce global cardiovascular mortality.
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