Evidence map›Paper›PMID 36192689›Full record

ArticleThe journal of headache and pain2022

Resting-state magnetoencephalographic oscillatory connectivity to identify patients with chronic migraine using machine learning.

Fu-Jung Hsiao, Wei-Ta Chen, Li-Ling Hope Pan, Hung-Yu Liu, Yen-Feng Wang, Shih-Pin Chen, Kuan-Lin Lai, Gianluca Coppola, Shuu-Jiun Wang

Abstract read
In one paragraph

Article in The journal of headache and pain, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  11. Hallmarks of primary headache: part 1 - migraine.The journal of headache and pain · 2024
    Review
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  17. Application of EEG in migraine.Frontiers in human neuroscience · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Fu-Jung HsiaoBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan. fujunghsiao@gmail.com.
Wei-Ta ChenBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan. wtchen@vghtpe.gov.tw.
Li-Ling Hope PanBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Hung-Yu LiuSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Yen-Feng WangSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Shih-Pin ChenBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Kuan-Lin LaiSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Gianluca CoppolaDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome Polo Pontino, Latina, Italy.
Shuu-Jiun WangBrain Research Center, National Yang Ming Chiao Tung University, Taipei, Taiwan.

Funding

Ministry of Science and Technology, Taiwan 108-2221-E-010-004Ministry of Science and Technology, Taiwan 108-2321-B-010-014-MY2Ministry of Science and Technology, Taiwan 109-2314-B-075 -050 -MY2
6 · The paper itself

Abstract

To identify and validate the neural signatures of resting-state oscillatory connectivity for chronic migraine (CM), we used machine learning techniques to classify patients with CM from healthy controls (HC) and patients with other pain disorders. The cross-sectional study obtained resting-state magnetoencephalographic data from 240 participants (70 HC, 100 CM, 35 episodic migraine [EM], and 35 fibromyalgia [FM]). Source-based oscillatory connectivity of relevant cortical regions was calculated to determine intrinsic connectivity at 1-40 Hz. A classification model that employed a support vector machine was developed using the magnetoencephalographic data to assess the reliability and generalizability of CM identification. In the findings, the discriminative features that differentiate CM from HC were principally observed from the functional interactions between salience, sensorimotor, and part of the default mode networks. The classification model with these features exhibited excellent performance in distinguishing patients with CM from HC (accuracy ≥ 86.8%, area under the curve (AUC) ≥ 0.9) and from those with EM (accuracy: 94.5%, AUC: 0.96). The model also achieved high performance (accuracy: 89.1%, AUC: 0.91) in classifying CM from other pain disorders (FM in this study). These resting-state magnetoencephalographic electrophysiological features yield oscillatory connectivity to identify patients with CM from those with a different type of migraine and pain disorder, with adequate reliability and generalizability.

Indexed as

FibromyalgiaMigraine DisordersBrainBrain MappingCross-Sectional StudiesHumansMachine LearningMagnetic Resonance ImagingPainReproducibility of ResultsChronic migraineMachine learningMagnetoencephalographyPain disordersResting-state oscillatory connectivity

Identifiers

PMID36192689
PMCPMC9531441

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.