Evidence map›Paper›PMID 36192672›Full record

ArticleBMC infectious diseases2022

Clinical malaria incidence and health seeking pattern in geographically heterogeneous landscape of western Kenya.

Wilfred Ouma Otambo, Patrick O Onyango, Kevin Ochwedo, Julius Olumeh, Shirley A Onyango, Pauline Orondo, Harrysone Atieli, Ming-Chieh Lee, Chloe Wang, Daibin Zhong and 6 more

Abstract read
In one paragraph

Article in BMC infectious diseases, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Wilfred Ouma OtamboDepartment of Zoology, Maseno University, Kisumu, Kenya. oumaotambo@gmail.com.
Patrick O OnyangoDepartment of Zoology, Maseno University, Kisumu, Kenya.
Kevin OchwedoInternational Centre of Excellence for Malaria Research, Tom Mboya University College-University of California Irvine Joint Lab, Homa Bay, Kenya.
Julius OlumehSchool of Natural and Environmental Science, Newcastle University, Newcastle Upon Tyne, UK.
Shirley A OnyangoInternational Centre of Excellence for Malaria Research, Tom Mboya University College-University of California Irvine Joint Lab, Homa Bay, Kenya.
Pauline OrondoInternational Centre of Excellence for Malaria Research, Tom Mboya University College-University of California Irvine Joint Lab, Homa Bay, Kenya.
Harrysone AtieliInternational Centre of Excellence for Malaria Research, Tom Mboya University College-University of California Irvine Joint Lab, Homa Bay, Kenya.
Ming-Chieh LeeProgram in Public Health, University of California Irvine, Irvine, CA, USA.
Chloe WangProgram in Public Health, University of California Irvine, Irvine, CA, USA.
Daibin ZhongProgram in Public Health, University of California Irvine, Irvine, CA, USA.
Andrew GithekoCentre for Global Health Research, Kenya Medical Research Institute, Kisumu, Kenya.
Guofa ZhouProgram in Public Health, University of California Irvine, Irvine, CA, USA.
John GithureInternational Centre of Excellence for Malaria Research, Tom Mboya University College-University of California Irvine Joint Lab, Homa Bay, Kenya.
Collins OumaDepartment of Biomedical Sciences and Technology, Maseno University, Kisumu, Kenya.
Guiyun YanProgram in Public Health, University of California Irvine, Irvine, CA, USA.
James KazuraDepartment of Pathology, School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Funding

Vector Biology of Invasive Anopheles stephensi in Rural to Urban Landscapes in EthiopiaU19AI129326 · NIAID · UNIVERSITY OF CALIFORNIA-IRVINE · PI Delenasaw Yewhalaw · 2017 to 2026
$19.9M
Research Training in Mosquito Genomics and Bioinformat*D43TW001505 · FIC · UNIVERSITY OF CALIFORNIA-IRVINE · PI Guiyun Yan · 2000 to 2026
$6.0M
FIC NIH HHS D43 TW001505NIAID NIH HHS U19 AI129326NIH HHS U19 AI129326 and D43 TW001505
6 · The paper itself

Abstract

backgroundMalaria remains a public health problem in Kenya despite sustained interventions deployed by the government. One of the major impediments to effective malaria control is a lack of accurate diagnosis and effective treatment. This study was conducted to assess clinical malaria incidence and treatment seeking profiles of febrile cases in western Kenya.

methodsActive case detection of malaria was carried out in three eco-epidemiologically distinct zones topologically characterized as lakeshore, hillside, and highland plateau in Kisumu County, western Kenya, from March 2020 to March 2021. Community Health Volunteers (CHVs) conducted biweekly visits to residents in their households to interview and examine for febrile illness. A febrile case was defined as an individual having fever (axillary temperature ≥ 37.5 °C) during examination or complaints of fever and other nonspecific malaria related symptoms 1-2 days before examination. Prior to the biweekly malaria testing by the CHVs, the participants' treatment seeking methods were based on their behaviors in response to febrile illness. In suspected malaria cases, finger-prick blood samples were taken and tested for malaria parasites with ultra-sensitive Alere

resultsOf the total 5838 residents interviewed, 2205 residents had high temperature or reported febrile illness in the previous two days before the visit. Clinical malaria incidence (cases/1000people/month) was highest in the lakeshore zone (24.3), followed by the hillside (18.7) and the highland plateau zone (10.3). Clinical malaria incidence showed significant difference across gender (χ

conclusionClinical malaria incidence remains highest in the Lakeshore (24.3cases/1000 people/month) despite high LLINs coverage (90%). The travel distance to the health facility, severity of disease and affordability were mainly associated with 80% of residents either self-medicating or doing nothing to alleviate their illness. The findings of this study suggest that the Ministry of Health should strengthen community case management of malaria by providing supportive supervision of community health volunteers to advocate for community awareness, early diagnosis, and treatment of malaria.

Indexed as

AntimalarialsMalariaChildFeverHumansIncidenceInfant, NewbornKenyaAntimalarialsActive case detectionHealth seeking behaviorKenyaMalaria incidenceSelf-medicationTraditional medicationUltrasensitive RDT

Identifiers

PMID36192672
PMCPMC9528858

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.