Evidence map›Paper›PMID 36192671›Full record

ArticleBMC oral health2022

Oxidative stress impairs the calcification ability of human dental pulp cells.

Satomi Shirawachi, Katsuhiro Takeda, Tomoya Naruse, Yohei Takahasi, Jun Nakanishi, Satoru Shindo, Hideki Shiba

Abstract read
In one paragraph

Article in BMC oral health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Satomi ShirawachiDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan.
Katsuhiro TakedaDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan. takepon@hiroshima-u.ac.jp.
Tomoya NaruseDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan.
Yohei TakahasiDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan.
Jun NakanishiDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan.
Satoru ShindoDepartment of Oral Sciences and Translational Research, College of Dental Medicine, Nova Southeastern University, Fort Lauderdale, FL, USA.
Hideki ShibaDepartment of Biological Endodontics, Graduate School of Biomedical and Health Sciences, Hiroshima University, 1-2-3 Kasumi, Minami-ku, Hiroshima, Hiroshima, 734-8553, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe relationship between internal root resorption and oxidative stress has not yet been reported. This study aimed to add molecular insight into internal root resorption. The present study was conducted to investigate the effect of hydrogen peroxide (H MATERIAL AND

methodshDPCs (Lonza, Basel, Switzerland) were exposed to H

resultsH

conclusionTo the best of our knowledge, this is the first study documenting the involvement of IP

Indexed as

Dental PulpRoot ResorptionAlkaline PhosphataseCell DifferentiationCell ProliferationCells, CulturedHumansHydrogen PeroxideInositolInositol 1,4,5-Trisphosphate ReceptorsOdontoblastsOxidative StressReactive Oxygen SpeciesRNA, MessengerAlkaline PhosphataseHydrogen PeroxideInositolInositol 1,4,5-Trisphosphate ReceptorsReactive Oxygen SpeciesRNA, Messenger2-aminoethyldiphenylborateHuman dental pulp cellsOxidative stress

Identifiers

PMID36192671
PMCPMC9531526

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.