Evidence map›Paper›PMID 36192569›Full record

Observational studyScientific reports2022

Prone positioning may increase lung overdistension in COVID-19-induced ARDS.

Michal Otáhal, Mikuláš Mlček, João Batista Borges, Glasiele Cristina Alcala, Dominik Hladík, Eduard Kuriščák, Leoš Tejkl, Marcelo Amato, Otomar Kittnar

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Michal Otáhal *Department of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic.
Mikuláš Mlček *Institute of Physiology, First Faculty of Medicine, Charles University, Albertov 5, 128 00, Prague, Czech Republic.
João Batista BorgesInstitute of Physiology, First Faculty of Medicine, Charles University, Albertov 5, 128 00, Prague, Czech Republic. joaobatistaborges8@gmail.com.
Glasiele Cristina AlcalaPulmonology Division, Cardiopulmonary Department, Heart Institute, University of Sao Paulo, São Paulo, Brazil.
Dominik HladíkDepartment of Anaesthesiology, Resuscitation and Intensive Medicine, First Faculty of Medicine, General University Hospital in Prague, Charles University, Prague, Czech Republic.
Eduard KuriščákInstitute of Physiology, First Faculty of Medicine, Charles University, Albertov 5, 128 00, Prague, Czech Republic.
Leoš TejklInstitute of Physiology, First Faculty of Medicine, Charles University, Albertov 5, 128 00, Prague, Czech Republic.
Marcelo AmatoPulmonology Division, Cardiopulmonary Department, Heart Institute, University of Sao Paulo, São Paulo, Brazil.
Otomar KittnarInstitute of Physiology, First Faculty of Medicine, Charles University, Albertov 5, 128 00, Prague, Czech Republic.
Charles University · CZCzech Academy of Sciences, Institute of Physiology · CZUniversidade de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Real-time effects of changing body position and positive end-expiratory pressure (PEEP) on regional lung overdistension and collapse in individual patients remain largely unknown and not timely monitored. The aim of this study was to individualize PEEP in supine and prone body positions seeking to reduce lung collapse and overdistension in mechanically ventilated patients with coronavirus disease (COVID-19)-induced acute respiratory distress syndrome (ARDS). We hypothesized that prone positioning with bedside titrated PEEP would provide attenuation of both overdistension and collapse. In this prospective observational study, patients with COVID-19-induced ARDS under mechanical ventilation were included. We used electrical impedance tomography (EIT) with decremental PEEP titration algorithm (PEEP

Indexed as

COVID-19Positive-Pressure RespirationPulmonary AtelectasisRespiratory Distress SyndromeHumansLungProne Position

Identifiers

PMID36192569
PMCPMC9528866
OpenAlexW4300864848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.