ArticleBrain structure & function2022
Stroke disconnectome decodes reading networks.
Article in Brain structure & function, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- What do we know about the Vertical Occipital Fasciculus? A systematic review.Brain structure & function · 2026Pooled it
- Individual differences in speech monitoring: Functional and structural correlates of delayed auditory feedback.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Translational network neuroscience: Nine roadblocks and possible solutions.Network neuroscience (Cambridge, Mass.) · 2025Article
- Tractometry of Human Visual White Matter Pathways in Health and Disease.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024Review
- Brain disconnections refine the relationship between brain structure and function.Brain structure & function · 2022Article
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Authors and funding
5 authors.
Funding
Abstract
Cognitive functional neuroimaging has been around for over 30 years and has shed light on the brain areas relevant for reading. However, new methodological developments enable mapping the interaction between functional imaging and the underlying white matter networks. In this study, we used such a novel method, called the disconnectome, to decode the reading circuitry in the brain. We used the resulting disconnection patterns to predict a typical lesion that would lead to reading deficits after brain damage. Our results suggest that white matter connections critical for reading include fronto-parietal U-shaped fibres and the vertical occipital fasciculus (VOF). The lesion most predictive of a reading deficit would impinge on the left temporal, occipital, and inferior parietal gyri. This novel framework can systematically be applied to bridge the gap between the neuropathology of language and cognitive neuroscience.
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Registered trials
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